(R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine

Base Information

• Chemical Name: (R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine
• CAS No.: 260550-89-8
• Molecular Formula: C16H23NO
• Molecular Weight: 245.37
• UNII: 5XG5HU8U55
• DSSTox Substance ID: DTXSID701027206
• Nikkaji Number: J1.579.462C
• Wikipedia: Benzofuranylpropylaminopentane
• Mol file: 260550-89-8.mol

Synonyms:260550-89-8;(R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine;(2r)-1-(1-benzofuran-2-yl)-n-propylpentan-2-amine;FPFS-1169 free base;R-(-)-Bpap;5XG5HU8U55;UNII-5XG5HU8U55;SCHEMBL2486381;(R)-(?)-BPAP;DTXSID701027206;AMY19206;(alphaR)-N,alpha-Dipropyl-2-benzofuranethanamine;r-(-)-1-(benzofuran-2-yl)-2-propylaminopentane;(2R)-1-(1-Benzofuran-2-yl)-N-propyl-2-pentanamine;[(2R)-1-(1-benzofuran-2-yl)pentan-2-yl](propyl)amine;(.ALPHA.R)-N,.ALPHA.-DIPROPYL-2-BENZOFURANETHANAMINE

Chemical Property of (R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine

Chemical Property:

• Boiling Point: 344.7±17.0 °C(Predicted)
• PKA: 10.34±0.29(Predicted)
• PSA: 25.17000
• Density: 0.991±0.06 g/cm3(Predicted)
• LogP: 4.53450
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 245.177964357
• Heavy Atom Count: 18
• Complexity: 231

Purity/Quality:

99% ^*data from raw suppliers

(R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCC(CC1=CC2=CC=CC=C2O1)NCCC
• Isomeric SMILES: CCC[C@H](CC1=CC2=CC=CC=C2O1)NCCC

Technology Process of (R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine

There total 48 articles about (R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(R)-N-{2-[1-(benzofuran-2-yl)pentyl]}propionamide (354583-01-0) → R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane (260550-89-8)

Guidance literature:

(R)-N-{2-[1-(benzofuran-2-yl)pentyl]}propionamide; With lithium aluminium tetrahydride; In diethyl ether; Heating;

With sodium fluoride; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1016/S0968-0896(00)00341-2

Reference yield: 68.0%

(R)-1-(2-benzofuran-2-yl)-2-N-propyl-p-toluenesulfonylaminopentane (354583-03-2) → R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane (260550-89-8)

Guidance literature:

With sodium naphthalenide; In 1,2-dimethoxyethane; at -78 ℃; for 0.5h;

DOI:10.1016/S0968-0896(00)00341-2

Reference yield: 67.9%

N-(2-(1-(benzofuran-2-yl))pentyl)propionamide (359415-04-6) → (-)-1-(benzofuran-2-yl)-2-propylaminopentane (260550-89-8)

Guidance literature:

With aluminium hydride; In diethyl ether; at 20 ℃; for 24h;

DOI:10.1016/S0968-0896(01)00002-5

upstream raw materials:

1-benzofurane

propyl bromide

N-(p-toluenesulfonyl)-2-propylaziridine

N-(2-(1-(benzofuran-2-yl))pentyl)propionamide