5-Cyclopropylisoxazole-4-carboxylic acid

Base Information

Chemical Name:5-Cyclopropylisoxazole-4-carboxylic acid
CAS No.:124845-04-1
Molecular Formula:C7H7NO3
Molecular Weight:153.137
Hs Code.:2934999090
European Community (EC) Number:625-705-6
DSSTox Substance ID:DTXSID70564402
Wikidata:Q82449097
Mol file:124845-04-1.mol

Synonyms:5-Cyclopropylisoxazole-4-carboxylic acid;124845-04-1;5-cyclopropyl-1,2-oxazole-4-carboxylic acid;4-Isoxazolecarboxylic acid, 5-cyclopropyl-;5-CYCLOPROPYLISOXAZOLE-4-CARBOXYLIC ACI;5-CYCLOPROPYLISOXAZOLE-4-CARBOXYLICACID;SCHEMBL1027062;DTXSID70564402;KIJMAOMSRMPYIY-UHFFFAOYSA-N;ZEA84504;MFCD06798100;AKOS009423618;AM86435;AS-65448;CS-0204847;5-Cyclopropylisoxazole-4-carboxylic acid, 95%;EN300-113062;N10119;5-CYCLOPROPYLISOXAZOLE-4-CARBOXYLIC ACI&;A921336;J-005175;F2173-0025;Z406694026

Suppliers and Price of 5-Cyclopropylisoxazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Cyclopropylisoxazole-4-carboxylic acid
1g
$ 310.00

Sigma-Aldrich
5-Cyclopropylisoxazole-4-carboxylic acid 95%
1g
$ 147.00

Sigma-Aldrich
5-Cyclopropylisoxazole-4-carboxylic acid 95%
5g
$ 475.00

Matrix Scientific
5-Cyclopropyl-1,2-oxazole-4-carboxylic acid 95%+
1g
$ 195.00

Matrix Scientific
5-Cyclopropyl-1,2-oxazole-4-carboxylic acid 95%+
5g
$ 636.00

Matrix Scientific
5-Cyclopropyl-1,2-oxazole-4-carboxylic acid 95%+
2.500g
$ 420.00

Crysdot
5-Cyclopropylisoxazole-4-carboxylic acid 95+%
1g
$ 220.00

Crysdot
5-Cyclopropylisoxazole-4-carboxylic acid 95+%
5g
$ 604.00

Chemenu
5-Cyclopropylisoxazole-4-carboxylic acid 95%
5g
$ 565.00

Chemenu
5-Cyclopropylisoxazole-4-carboxylic acid 95%
1g
$ 206.00

Total 12 raw suppliers

Chemical Property of 5-Cyclopropylisoxazole-4-carboxylic acid

Chemical Property:

Vapor Pressure:0.000159mmHg at 25°C
Melting Point:161-165 °C(lit.)
Boiling Point:317.6°C at 760 mmHg
Flash Point:145.9°C
PSA：63.33000
Density:1.445g/cm³
LogP:1.25020
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:153.042593085
Heavy Atom Count:11
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

5-Cyclopropylisoxazole-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): R22:;
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1C2=C(C=NO2)C(=O)O

Technology Process of 5-Cyclopropylisoxazole-4-carboxylic acid

There total 2 articles about 5-Cyclopropylisoxazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.13%

: 32249-35-7
methyl 3-cyclopropyl-3-oxopropanoate

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 124845-04-1
5-cyclopropylisoxazole-4-carboxylic acid

Guidance literature:: methyl 3-cyclopropyl-3-oxopropanoate; N,N-dimethyl-formamide dimethyl acetal; at 60 ℃; for 20h;

With hydroxylamine hydrochloride; In methanol; water; at 60 ℃; for 1.5h;

With hydrogenchloride; In acetic acid; at 100 ℃; for 4h;
DOI:10.1016/j.molstruc.2020.128628