3-(2-Chloro-4-fluorophenyl)propanoic acid

Base Information

Chemical Name:3-(2-Chloro-4-fluorophenyl)propanoic acid
CAS No.:174603-38-4
Molecular Formula:C9H8ClFO2
Molecular Weight:202.613
Hs Code.:2916399090
DSSTox Substance ID:DTXSID10472158
Wikidata:Q82300949
Mol file:174603-38-4.mol

Synonyms:174603-38-4;3-(2-chloro-4-fluorophenyl)propanoic acid;3-(2-CHLORO-4-FLUORO-PHENYL)-PROPIONIC ACID;Benzenepropanoic acid, 2-chloro-4-fluoro-;MFCD06656905;3-(2-Chloro-4-fluorophenyl)propionic acid;3-(2-chloro-4-fluoro-phenyl)propanoic Acid;SCHEMBL5045620;DTXSID10472158;WLZ3271;CWLAMJYAQMNGPA-UHFFFAOYSA-N;AMY16158;AKOS009556336;3-(2-chloro-4-fluorophenyl)propanoicacid;DS-13662;SY014686;CS-0074161;FT-0660174;EN300-98608;F14499;A811667;2-Chloro-4-fluoro-benzenepropionic acid, AldrichCPR;F9994-0613;Z426022268

Suppliers and Price of 3-(2-Chloro-4-fluorophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-Chloro-4-fluoro-phenyl)propionicAcid
100mg
$ 60.00

SynQuest Laboratories
3-(2-Chloro-4-fluorophenyl)propanoic acid
5 g
$ 807.00

Sigma-Aldrich
2-Chloro-4-fluoro-benzenepropionic acid Aldrich
1g
$ 168.00

Labseeker
3-(2-Chloro-4-fluoro-phenyl)-propionicacid 95
5g
$ 2933.00

Crysdot
3-(2-Chloro-4-fluorophenyl)propanoicacid 95+%
5g
$ 353.00

Chemenu
3-(2-Chloro-4-fluorophenyl)propanoicacid 95%
5g
$ 360.00

American Custom Chemicals Corporation
3-(2-CHLORO-4-FLUORO-PHENYL)-PROPIONIC ACID 95.00%
5G
$ 1437.98

Ambeed
3-(2-Chloro-4-fluorophenyl)propanoicacid 97%
250mg
$ 27.00

Ambeed
3-(2-Chloro-4-fluorophenyl)propanoicacid 97%
1g
$ 70.00

Alichem
3-(2'-Chloro-4'-fluorophenyl)propionicacid
500mg
$ 806.85

Total 22 raw suppliers

Chemical Property of 3-(2-Chloro-4-fluorophenyl)propanoic acid

Chemical Property:

PSA：37.30000
LogP:2.49630
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:202.0196853
Heavy Atom Count:13
Complexity:187

Purity/Quality:

97% ^*data from raw suppliers

3-(2-Chloro-4-fluoro-phenyl)propionicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)Cl)CCC(=O)O

Technology Process of 3-(2-Chloro-4-fluorophenyl)propanoic acid

There total 3 articles about 3-(2-Chloro-4-fluorophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 174603-37-3
3-(2-chloro-4-fluorophenyl)-2-propenoic acid

: 174603-38-4
3-(2-chloro-4-fluorophenyl)propanoic acid

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol;
DOI:10.1021/jm020068k

Reference yield:

: 84194-36-5
2-chloro-4-fluorobenzaldehyde

: 174603-38-4
3-(2-chloro-4-fluorophenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / pyridine; piperidine / 18 h / 70 °C

2: 98 percent / H₂ / platinum oxide / aq. ethanol

With piperidine; pyridine; hydrogen; platinum(IV) oxide; In ethanol; 1: Knoevenagel reaction;
DOI:10.1021/jm020068k