2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid

Base Information

Chemical Name:2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid
CAS No.:121219-20-3
Molecular Formula:C12H17BF2O3
Molecular Weight:258.07
Hs Code.:2931900090
DSSTox Substance ID:DTXSID80376831
Wikidata:Q82165745
Mol file:121219-20-3.mol

Synonyms:2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid;121219-20-3;(2,3-difluoro-4-hexoxyphenyl)boronic acid;2,3-Difluoro-4-hexyloxybenzeneboronic acid;SCHEMBL2510510;DTXSID80376831;MFCD06656273;AKOS015854243;AB25505;2,3-Difluoro-4-hexyloxyphenylboronicacid;BS-26473;CS-0175910;FT-0729359;(2,3-Difluoro-4-(hexyloxy)phenyl)boronic acid;E89997;A891837;(4-CHLORO-2-ISOPROPYL-5-METHYL-PHENOXY)-ACETICACID

Suppliers and Price of 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Difluoro-4-(n-hexyloxy)phenylboronicacid
250mg
$ 55.00

SynQuest Laboratories
2,3-Difluoro-4-hexyloxybenzeneboronic acid
1 g
$ 141.00

SynQuest Laboratories
2,3-Difluoro-4-hexyloxybenzeneboronic acid
5 g
$ 493.00

Crysdot
2,3-Difluoro-4-(N-hexyloxy)phenylboronicacid 95+%
10g
$ 322.00

Crysdot
2,3-Difluoro-4-(N-hexyloxy)phenylboronicacid 95+%
25g
$ 640.00

Chemenu
2,3-Difluoro-4-(N-hexyloxy)phenylboronicacid 98%
25g
$ 673.00

Chemenu
2,3-Difluoro-4-(N-hexyloxy)phenylboronicacid 98%
5g
$ 178.00

Apolloscientific
2,3-Difluoro-4-hexyloxybenzeneboronicacid
5g
$ 308.00

Apolloscientific
2,3-Difluoro-4-hexyloxybenzeneboronicacid
1g
$ 88.00

AOBChem
2,3-Difluoro-4-(n-hexyloxy)phenylboronicacid 97%
5g
$ 164.00

Total 23 raw suppliers

Chemical Property of 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid

Chemical Property:

Vapor Pressure:4.42E-06mmHg at 25°C
Boiling Point:368.5°C at 760 mmHg
Flash Point:176.7°C
PSA：49.69000
Density:1.16g/cm³
LogP:1.60370
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:258.1238809
Heavy Atom Count:18
Complexity:231

Purity/Quality:

97% ^*data from raw suppliers

2,3-Difluoro-4-(n-hexyloxy)phenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C(=C(C=C1)OCCCCCC)F)F)(O)O

Technology Process of 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid

There total 8 articles about 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₂₉BF₂O₃

: 121219-20-3
2,3-fluoro-4-(n-hexyloxy)phenylboronic acid

Guidance literature:: With hydrogenchloride; at 20 ℃; for 1h;
DOI:10.1039/a902351h

Reference yield:

: 111-25-1
1-bromo-hexane

: 121219-20-3
2,3-fluoro-4-(n-hexyloxy)phenylboronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: K₂CO₃ / acetone / 48 h / Heating

2.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

2.2: hexane; tetrahydrofuran / -78 - 20 °C

3.1: 10 percent aq. HCl / 1 h / 20 °C

With hydrogenchloride; n-butyllithium; potassium carbonate; In tetrahydrofuran; hexane; acetone; 1.1: Alkylation / 2.1: Metallation / 2.2: Substitution / 3.1: Hydrolysis;
DOI:10.1039/a902351h

Reference yield:

: 367-11-3
ortho-difluorobenzene

: 121219-20-3
2,3-fluoro-4-(n-hexyloxy)phenylboronic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

1.2: hexane; tetrahydrofuran / -78 - 20 °C

2.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C

3.1: 100 percent / 10 percent aq. H₂O₂ / diethyl ether / 2.5 h / Heating

4.1: K₂CO₃ / acetone / 48 h / Heating

5.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

5.2: hexane; tetrahydrofuran / -78 - 20 °C

6.1: 10 percent aq. HCl / 1 h / 20 °C

With hydrogenchloride; n-butyllithium; dihydrogen peroxide; potassium carbonate; In tetrahydrofuran; diethyl ether; hexane; acetone; 1.1: Metallation / 1.2: Substitution / 2.1: Hydrolysis / 3.1: Oxidation / 4.1: Alkylation / 5.1: Metallation / 5.2: Substitution / 6.1: Hydrolysis;
DOI:10.1039/a902351h