3-(3,5-Dimethoxy-phenyl)-propan-1-OL

Base Information

• Chemical Name: 3-(3,5-Dimethoxy-phenyl)-propan-1-OL
• CAS No.: 1080-05-3
• Molecular Formula: C11H16O3
• Molecular Weight: 196.246
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID20462626
• Nikkaji Number: J1.754.674K
• Wikidata: Q82287187
• Mol file: 1080-05-3.mol

Synonyms:3-(3,5-dimethoxyphenyl)propan-1-ol;1080-05-3;3-(3,5-DIMETHOXY-PHENYL)-PROPAN-1-OL;3-(3,5-dimethoxyphenyl)-1-propanol;SCHEMBL224550;DTXSID20462626;YSXABKVXIGREIB-UHFFFAOYSA-N;BAA08005;AKOS005217813;SB84712

Chemical Property of 3-(3,5-Dimethoxy-phenyl)-propan-1-OL

Chemical Property:

• Vapor Pressure: 6.42E-05mmHg at 25°C
• Boiling Point: 331°C at 760 mmHg
• Flash Point: 154°C
• PSA: 38.69000
• Density: 1.064g/cm³
• LogP: 1.62870
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 196.109944368
• Heavy Atom Count: 14
• Complexity: 138

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(3,5-Dimethoxyphenyl)propan-1-ol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1)CCCO)OC

Technology Process of 3-(3,5-Dimethoxy-phenyl)-propan-1-OL

There total 22 articles about 3-(3,5-Dimethoxy-phenyl)-propan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-(3,5-dimethoxyphenyl)propionic acid ethyl ester (54901-09-6) → 3-(3,5-dimethoxyphenyl)-1-propanol (1080-05-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2.5h;

DOI:10.1081/SCC-120004271

Reference yield: 88.0%

3-(3,5-dimethoxyphenyl)propionic acid (717-94-2) → 3-(3,5-dimethoxyphenyl)-1-propanol (1080-05-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 25 ℃; for 24h;

DOI:10.1080/00397911.2013.841939

Reference yield: 80.0%

1-<3-Brom-propoxy>-3,5-dimethoxy-benzol (3245-56-5) → 3-(3,5-dimethoxyphenyl)-1-propanol (1080-05-3) + 1-(3,5-dimethoxyphenoxy)propane

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 1h; Heating;

DOI:10.1016/S0040-4039(00)77609-X

upstream raw materials:

3-(3,5-dimethoxyphenyl)propionic acid

1-<3-Brom-propoxy>-3,5-dimethoxy-benzol

Methyl 3-(3',5'-dimethoxyphenyl)propionate

(E)-ethyl 3-(3,5-dimethoxyphenyl)acrylate

Downstream raw materials:

3-(3,5-dimethoxyphenyl)-1-propanal

5-(3,5-dimethoxyphenyl)pentanoic acid

1-(3,5-dimethoxyphenyl)octane-5,7-dione

benzyl 6,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-ylcarbamate