2-Bromo-5-chloroterephthalic acid

Base Information

Chemical Name:2-Bromo-5-chloroterephthalic acid
CAS No.:500550-60-7
Molecular Formula:C8H4BrClO4
Molecular Weight:279.473
Hs Code.:2917399590
NSC Number:126423
DSSTox Substance ID:DTXSID20298841
Wikidata:Q72452376
Mol file:500550-60-7.mol

Synonyms:2-bromo-5-chloroterephthalic acid;500550-60-7;NSC 126423;2-bromo-5-chlorobenzene-1,4-dicarboxylic acid;2-Bromo-5-chloroterephthalicacid;2-bromo-5-chloro-terephthalic acid;NSC126423;SCHEMBL6858908;DTXSID20298841;AKOS015890289;NSC-126423;DS-16056;FT-0656839

Suppliers and Price of 2-Bromo-5-chloroterephthalic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Bromo-5-chloroterephthalic acid 95+%
5g
$ 615.00

Matrix Scientific
2-Bromo-5-chloroterephthalic acid 95+%
1g
$ 174.00

Crysdot
2-Bromo-5-chloroterephthalicacid 95+%
10g
$ 405.00

Crysdot
2-Bromo-5-chloroterephthalicacid 95+%
5g
$ 270.00

Crysdot
2-Bromo-5-chloroterephthalicacid 95+%
1g
$ 90.00

American Custom Chemicals Corporation
2-BROMO-5-CHLOROTEREPHTHALIC ACID 95.00%
10G
$ 1334.03

American Custom Chemicals Corporation
2-BROMO-5-CHLOROTEREPHTHALIC ACID 95.00%
5G
$ 909.56

Alichem
2-Bromo-5-chloroterephthalicacid
10g
$ 654.00

Alichem
2-Bromo-5-chloroterephthalicacid
5g
$ 427.28

AK Scientific
2-Bromo-5-chloroterephthalicacid
5g
$ 880.00

Total 24 raw suppliers

Chemical Property of 2-Bromo-5-chloroterephthalic acid

Chemical Property:

Vapor Pressure:5.95E-08mmHg at 25°C
Boiling Point:424.2°C at 760 mmHg
Flash Point:210.3°C
PSA：74.60000
Density:1.959g/cm³
LogP:2.49890
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:277.89815
Heavy Atom Count:14
Complexity:258

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-5-chloroterephthalic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1Cl)C(=O)O)Br)C(=O)O

Technology Process of 2-Bromo-5-chloroterephthalic acid

There total 2 articles about 2-Bromo-5-chloroterephthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85072-44-2
1-bromo-4-chloro-2,5-dimethylbenzene

: 500550-60-7
2-bromo-5-chloro-terephthalic acid

Guidance literature:: With potassium permanganate; In water; tert-butyl alcohol; for 19h; Reflux;
DOI:10.1021/acs.joc.6b00340

Reference yield:

: 95-72-7
2-chloro-1,4-dimethyl-benzene

: 500550-60-7
2-bromo-5-chloro-terephthalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; bromine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere; Darkness

2: potassium permanganate / water; tert-butyl alcohol / 19 h / Reflux

With potassium permanganate; bromine; iodine; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1021/acs.joc.6b00340

Reference yield:

: 500550-60-7
2-bromo-5-chloro-terephthalic acid

: 865-47-4
potassium tert-butylate

: 2-bromo-5-chloro-p-benzenedicarboxylic acid ditert-butyl ester

Guidance literature:: 2-bromo-5-chloro-terephthalic acid; With oxalyl dichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h;

potassium tert-butylate; In tetrahydrofuran; at 20 ℃; Cooling with ice;