3-(p-Chlorophenethyl)picolinonitrile

Base Information

Chemical Name:3-(p-Chlorophenethyl)picolinonitrile
CAS No.:31255-55-7
Molecular Formula:C₁₄H₁₁ClN₂
Molecular Weight:242.708
Hs Code.:
Mol file:31255-55-7.mol

Synonyms:2-Cyano-3-(p-chlorophenethyl)-pyridin;3-[2-(4-Chloro-phenyl)-ethyl]-pyridine-2-carbonitrile;

Suppliers and Price of 3-(p-Chlorophenethyl)picolinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 3-(p-Chlorophenethyl)picolinonitrile

Chemical Property:

Melting Point:73 - 74 °C
Boiling Point:375.7±32.0 °C(Predicted)
PKA:-0.14±0.10(Predicted)
PSA：36.68000
Density:1.23
LogP:3.39188

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(p-Chlorophenethyl)picolinonitrile

There total 4 articles about 3-(p-Chlorophenethyl)picolinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-[2-(4-Chloro-phenyl)-ethyl]-pyridine-2-carboxylic acid tert-butylamide

: 31255-55-7
3-(4-chloro-phenethyl)-pyridine-2-carbonitrile

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1021/jm00105a069

Reference yield:

: 32998-95-1
N-tert-butyl-3-methylpyridine-2-carboxamide

: 31255-55-7
3-(4-chloro-phenethyl)-pyridine-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, -40 deg C

2: POCl₃ / Heating

With n-butyllithium; trichlorophosphate;
DOI:10.1021/jm00105a069

Reference yield:

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 31255-55-7
3-(4-chloro-phenethyl)-pyridine-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, -40 deg C

2: POCl₃ / Heating

With n-butyllithium; trichlorophosphate;
DOI:10.1021/jm00105a069