Ethyl 2-acetylisonicotinate

Base Information

Chemical Name:Ethyl 2-acetylisonicotinate
CAS No.:25028-32-4
Molecular Formula:C10H11NO3
Molecular Weight:C10H11NO3
Hs Code.:2933399090
Mol file:25028-32-4.mol

Synonyms:Ethyl 2-acetylisonicotinate

Suppliers and Price of Ethyl 2-acetylisonicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-acetylisonicotinate 95+%
5g
$ 460.00

Chemenu
ethyl2-acetylisonicotinate 95%
5g
$ 435.00

American Custom Chemicals Corporation
ETHYL-2-ACETYLISONICOTINATE 95.00%
5MG
$ 500.98

Alfa Aesar
Ethyl 2-acetylisonicotinate, 96%
5g
$ 276.00

Alfa Aesar
Ethyl 2-acetylisonicotinate, 96%
1g
$ 83.40

AK Scientific
Ethyl2-acetylisonicotinate
5g
$ 304.00

Total 11 raw suppliers

Chemical Property of Ethyl 2-acetylisonicotinate

Chemical Property:

Vapor Pressure:0.000597mmHg at 25°C
Melting Point:52-55℃
Boiling Point:310.5°C at 760 mmHg
PKA:0.48±0.10(Predicted)
Flash Point:141.6°C
PSA：56.26000
Density:1.145g/cm³
LogP:1.46090
Storage Temp.:Inert atmosphere,Room Temperature

Purity/Quality:

99.0% ^*data from raw suppliers

Ethyl2-acetylisonicotinate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 2-acetylisonicotinate

There total 4 articles about Ethyl 2-acetylisonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1570-45-2
isonicotinic acid ethylester

: 123-63-7
paracetaldehyde

: 25028-32-4
ethyl 2-acetylpyridine-4-carboxylate

Guidance literature:: With tert.-butylhydroperoxide; ferrous(II) sulfate heptahydrate; trifluoroacetic acid; for 4h; Reflux;
DOI:10.1016/j.ica.2022.120848

Reference yield: 60.0%

: 1570-45-2
isonicotinic acid ethylester

: 123-63-7
paracetaldehyde

: ethyl 2,5-diacetylisonicotinate

: 25028-32-4
ethyl 2-acetylpyridine-4-carboxylate

Guidance literature:: With tert.-butylhydroperoxide; ferrous(II) sulfate heptahydrate; trifluoroacetic acid; In acetonitrile; for 4h; Reflux;
DOI:10.1016/j.tet.2015.06.029

Reference yield:

: 55-22-1
pyridine-4-carboxylic acid

: 25028-32-4
ethyl 2-acetylpyridine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 6 h / Reflux

2: ferrous(II) sulfate heptahydrate; trifluoroacetic acid; tert.-butylhydroperoxide / acetonitrile / 4 h / Reflux

With tert.-butylhydroperoxide; ferrous(II) sulfate heptahydrate; sulfuric acid; trifluoroacetic acid; In acetonitrile;
DOI:10.1039/c4dt01598c