N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine

Base Information

Chemical Name:N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine
CAS No.:101968-85-8
Molecular Formula:C11H22N2O3
Molecular Weight:230.307
Hs Code.:
Mol file:101968-85-8.mol

Synonyms:L-valine, N-[[(1,1-dimethylethyl)amino]carbonyl]-3-methyl-; N-(tert-Butylcarbamoyl)-3-methyl-L-valine; (S)-2-(3-tert-Butylureido)-3,3-dimethylbutanoic acid; N-tert-Butylcarbamoyl-L-tert-leucine; Boceprevir Intermediate 4

Suppliers and Price of N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-tert-Butylcarbamoyl-L-tert-leucine
100mg
$ 1320.00

TCI Chemical
N-tert-Butylcarbamoyl-L-tert-leucine >98.0%(HPLC)(T)
1g
$ 123.00

Medical Isotopes, Inc.
N-tert-Butylcarbamoyl-L-tert-leucine
100 mg
$ 2200.00

Crysdot
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoicacid 98%
250mg
$ 72.00

Crysdot
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoicacid 98%
1g
$ 110.00

Chemenu
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoicacid 98%
1g
$ 405.00

Biosynth Carbosynth
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoic acid
1 Kg
$ 1200.00

Biosynth Carbosynth
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoic acid
500 g
$ 800.00

Biosynth Carbosynth
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoic acid
250 g
$ 600.00

Biosynth Carbosynth
(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoic acid
100 g
$ 500.00

Total 47 raw suppliers

Chemical Property of N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine

Chemical Property:

Vapor Pressure:8.74E-08mmHg at 25°C
Melting Point:182 °C(dec.)
Refractive Index:1.472
Boiling Point:407.6°C at 760 mmHg
PKA:4.28±0.10(Predicted)
Flash Point:200.3°C
PSA：81.92000
Density:1.047g/cm³
LogP:2.17870
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Methanol

Purity/Quality:

97% ^*data from raw suppliers

N-tert-Butylcarbamoyl-L-tert-leucine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Reagent in the preparation of therapeutic agents.

Technology Process of N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine

There total 5 articles about N-[[(1,1-DiMethylethyl)aMino]carbonyl]-3-Methyl-L-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 20859-02-3
L-tert-Leucine

: 1609-86-5
Tert-butyl isocyanate

: 101968-85-8,1187162-85-1
(S)-2-(3-(tert-butyl)ureido)-3,3-dimethylbutanoic acid

Guidance literature:: L-tert-Leucine; With sodium hydroxide; In water; pH=11.5;

Tert-butyl isocyanate; In water; pH=9.3; Cooling with ice;

Reference yield: 82.0%

: 20859-02-3
L-tert-Leucine

: 75-64-9
tert-butylamine

: 530-62-1
1,1'-carbonyldiimidazole

: 101968-85-8,1187162-85-1
(S)-2-(3-(tert-butyl)ureido)-3,3-dimethylbutanoic acid

Guidance literature:: tert-butylamine; 1,1'-carbonyldiimidazole; In toluene; at 0 - 5 ℃;

L-tert-Leucine; With sodium hydroxide; In water; toluene; at 5 - 30 ℃;
DOI:10.1021/op500065t

Reference yield:

: (S)-trimethylsilyl 2-amino-3,3-dimethylbutanoate

: 10017-37-5
tert-butylamine hydrochloride

: 101968-85-8,1187162-85-1
(S)-2-(3-(tert-butyl)ureido)-3,3-dimethylbutanoic acid

Guidance literature:: (S)-trimethylsilyl 2-amino-3,3-dimethylbutanoate; tert-butylamine hydrochloride; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; dichloromethane; at 25 - 30 ℃; for 13.5h;

With hydrogenchloride; In tetrahydrofuran; dichloromethane; water; for 0.25h; pH=2.5;