5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene

Base Information

Chemical Name:5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene
CAS No.:208338-50-5
Molecular Formula:C22H29F5O
Molecular Weight:404.457076
Hs Code.:
European Community (EC) Number:606-647-0
DSSTox Substance ID:DTXSID50943074
Nikkaji Number:J2.259.729I,J1.945.899G
Mol file:208338-50-5.mol

Synonyms:208338-50-5;5-[Difluoro(4'-propyl[1,1'-bicyclohexyl]-4-yl)methoxy]-1,2,3-trifluorobenzene;5-[difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene;Benzene, 5-[difluoro[(trans,trans)-4'-propyl[1,1'-bicyclohexyl]-4-yl]methoxy]-1,2,3-trifluoro-;(trans,trans)-4-(Difluoro(3,4,5-trifluorophenoxy)methyl)-4'-propyl-1,1'-bi(cyclohexane);4-[DIFLUORO(3,4,5-TRIFLUOROPHENOXY)METHYL]-4'-PROPYLBICYCLOHEXYL;5-[DIFLUORO[(TRANS,TRANS)-4'-PROPYL[1,1'-BICYCLOHEXYL]-4-YL]METHOXY]-1,2,3-TRIFLUOROBENZENE;SCHEMBL6402958;SCHEMBL6402962;SCHEMBL6402964;SCHEMBL7525062;DTXSID50943074;QCRXXWNFJYKLHB-UHFFFAOYSA-N;MFCD20488040;AKOS032953818;5-[difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluoro-benzene;AS-75840;FT-0687692;NS00134157;D92954;A855187;J-516611;4-[difluoro(3,4,5-trifluorophenoxy)Methyl]-4'-propyl-1,1'-bi(cyclohexyl);1-(trans-4-(trans-4-propylcyclohexyl)-cyclohexyldifluoromethoxy)-3,4,5-trifluorobenzene;5-[difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1, 2, 3-trifluorobenzene;5-[Difluoro[(trans,trans)-4-propyl[1,1-bicyclohexyl]-4-yl]methoxy]-1,2,3-trifluorobenzene;(1r,1's,4r,4'r)-4-[difluoro(3,4,5-trifluorophenoxy)methyl]-4'-propyl-1,1'-bi(cyclohexane);(1r,1's,4r,4'r)-4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-4'-propyl-1,1'-bi(cyclohexyl)

Suppliers and Price of 5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 50 raw suppliers

Chemical Property of 5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene

Chemical Property:

Vapor Pressure:0-0Pa at 20-50℃
Boiling Point:408.7±40.0 °C(Predicted)
Flash Point:209.8oC
PSA：9.23000
Density:1.157±0.06 g/cm3(Predicted)
LogP:7.48840
XLogP3:9.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:404.21385635
Heavy Atom Count:28
Complexity:460

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1CCC(CC1)C2CCC(CC2)C(OC3=CC(=C(C(=C3)F)F)F)(F)F

Technology Process of 5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene

There total 6 articles about 5-[Difluoro-[4-(4-propylcyclohexyl)cyclohexyl]methoxy]-1,2,3-trifluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(4-(trans-4-propylcyclohexyl)cyclohexene-1-yl-difluoromethoxy)-3,4,5-trifluorobenzene as colorless crystals

: 208338-50-5
1-(trans-4-(trans-4-propylcyclohexyl)-cyclohexyldifluoromethoxy)-3,4,5-trifluorobenzene

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethanol; toluene; at 20 ℃; for 5h;

Reference yield:

: 208530-85-2
1-(4-(trans-4-propylcyclohexyl)cyclohexene-1-yl-difluoromethoxy)-3,4,5-trifluorobenzene

: 208338-50-5
1-(trans-4-(trans-4-propylcyclohexyl)-cyclohexyldifluoromethoxy)-3,4,5-trifluorobenzene

Guidance literature:: palladium-carbon;

Reference yield:

: 82832-73-3
4-(trans-4-n-propylcyclohexyl)cyclohexanone

: 208338-50-5
4-[difluoro-(3,4,5-trifluoro-phenoxy)-methyl]-4'-propyl-bicyclohexyl

Guidance literature:: Multi-step reaction with 4 steps

1: (Et₂N)3P

2: Br₂

3: K₂CO₃ / dimethylformamide

4: H₂ / Pd/C

With hydrogen; bromine; potassium carbonate; hexaethylphosphoric triamide; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1080/15421400490434919