Methyl 2-(piperazin-2-yl)acetate

Base Information

Chemical Name:Methyl 2-(piperazin-2-yl)acetate
CAS No.:368441-98-9
Molecular Formula:C7 H14 N2 O2
Molecular Weight:158.2
Hs Code.:2933599090
DSSTox Substance ID:DTXSID90378846
Mol file:368441-98-9.mol

Synonyms:Methyl 2-(piperazin-2-yl)acetate;368441-98-9;Methyl 2-piperazin-2-ylacetate;Methyl piperazine-2-acetate;methyl piperazin-2-ylacetate;2-Piperazineaceticacid,methylester(9CI);SCHEMBL122593;DTXSID90378846;Methyl2-(piperazin-2-yl)acetate;2-Piperazineaceticacid methylester;LFEGEWHLBLLABZ-UHFFFAOYSA-N;MFCD16660173;s11350;FT-0768410;methyl 2-piperazin-2-ylacetate,dihydrochloride

Suppliers and Price of Methyl 2-(piperazin-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl2-(piperazin-2-yl)acetate 95+%
1g
$ 353.00

Chemenu
methyl2-(piperazin-2-yl)acetate 95%
1g
$ 333.00

American Custom Chemicals Corporation
METHYL-2-(PIPERAZIN-2-YL)ACETATE 95.00%
5MG
$ 498.08

Alichem
Methyl2-(piperazin-2-yl)acetate
1g
$ 400.00

AccelPharmtech
2-Piperazineaceticacidmethylester 97.00%
25G
$ 11400.00

AccelPharmtech
2-Piperazineaceticacidmethylester 97.00%
5G
$ 6050.00

AccelPharmtech
2-Piperazineaceticacidmethylester 97.00%
1G
$ 3510.00

Total 22 raw suppliers

Chemical Property of Methyl 2-(piperazin-2-yl)acetate

Chemical Property:

PSA：50.36000
LogP:-0.23150
Storage Temp.:2-8°C
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:158.105527694
Heavy Atom Count:11
Complexity:138

Purity/Quality:

99%, ^*data from raw suppliers

Methyl2-(piperazin-2-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1CNCCN1

Technology Process of Methyl 2-(piperazin-2-yl)acetate

There total 6 articles about Methyl 2-(piperazin-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 183742-32-7
1,4-dibenzyl-2-methoxycarbonylmethylpiperazine

: 368441-98-9
methyl piperazin-2-ylacetate

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 24h; under 2585.74 Torr;
DOI:10.1021/jm061319i

Reference yield:

: 24225-89-6
2-chloromethyl-1,4-bis(phenylmethyl)piperazine

: 368441-98-9
methyl piperazin-2-ylacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / 7 h / Heating / reflux

2.1: methanol; sulfuric acid / Heating / reflux

2.2: pH 9

3.1: hydrogen / palladium(II) hydroxide/carbon / 15 h / 2585.81 Torr

With methanol; sulfuric acid; hydrogen; palladium(II) hydroxide/carbon; In ethanol;

Reference yield:

: 72351-59-8
ethyl 1,4-dibenzylpiperazin-2-carboxylate

: 368441-98-9
methyl piperazin-2-ylacetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 20.25 h / 20 °C

2.1: thionyl chloride / chloroform / 15.08 h / 0 - 20 °C / Heating / reflux

3.1: ethanol / 7 h / Heating / reflux

4.1: methanol; sulfuric acid / Heating / reflux

4.2: pH 9

5.1: hydrogen / palladium(II) hydroxide/carbon / 15 h / 2585.81 Torr

With methanol; lithium aluminium tetrahydride; thionyl chloride; sulfuric acid; hydrogen; palladium(II) hydroxide/carbon; In tetrahydrofuran; ethanol; chloroform;