72351-59-8

Basic information

• Product Name: Ethyl 1,4-dibenzylpiperazine-2-carboxylate
• Synonyms: BUTTPARK 32\04-68;ETHYL 1,4-DIBENZYLPIPERAZINE-2-CARBOXYLATE;1,4-dibenzylpiperazine-2-carboxylicacidethylester;2-Piperazinecarboxylic acid, 1,4-bis(phenylMethyl)-, ethyl ester;ethyl 1,4-diphenethylpiperazine-2-carboxylate
• CAS NO: 72351-59-8
• Molecular Formula: C₂₁H₂₆N₂O₂
• Molecular Weight: 338.44
• Product Categories: Piperazine series
• Mol File: 72351-59-8.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 200 °C
• Flash Point: 221.1 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 5.2E-08mmHg at 25°C
• Refractive Index: 1.579
• PKA: 5.88±0.10(Predicted)
• CAS DataBase Reference: Ethyl 1,4-dibenzylpiperazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 1,4-dibenzylpiperazine-2-carboxylate(72351-59-8)
• EPA Substance Registry System: Ethyl 1,4-dibenzylpiperazine-2-carboxylate(72351-59-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• Hazardous Substances Data: 72351-59-8(Hazardous Substances Data)

Usage

Uses

Ethyl 1,4-Dibenzylpiperazine-2-carboxylate is one of the reactants in preparation of (benzyl)(alkyl)(imidazolyl)piperazines and isoteric analogs.

InChI:InChI=1/C21H26N2O2/c1-2-25-21(24)20-17-22(15-18-9-5-3-6-10-18)13-14-23(20)16-19-11-7-4-8-12-19/h3-12,20H,2,13-17H2,1H3

Upstream product

• 140-28-3 N,N'-Dibenzylethylenediamine 
• 104-71-2 N,N'-bis(benzyliden)ethylendiamine 
• 100-52-7 benzaldehyde 
• 644-33-7 N,N'-ethanediyl-bis-benzamide 
• 3674-13-3 2,3-dibromopropionic acid ethyl ester 
• 14165-27-6 N,N-dibenzylethylenediamine 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 769159-55-9 1,4-dibenzyl-2-[1,2,4]triazol-1-ylmethylpiperazine 
• 368441-98-9 methyl piperazin-2-ylacetate 
• 183742-32-7 1,4-dibenzyl-2-methoxycarbonylmethylpiperazine 
• 129798-91-0 ethyl piperazine-2-carboxylate dihydrochloride 
• 94437-04-4 1,4-dibenzyl-2-hydroxypiperazine 
• 117810-52-3 2,3,4,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-6-one 
• 17532-22-8 (1,4-dibenzyl-piperazin-2-yl)-diphenyl-methanol 
• 2465-79-4 2-(piperazin-2-yl)acetonitrile 
• 111760-36-2 2-fluoromethyl-1,4-di-phenylmethyl piperazine 
• 1310452-84-6 1,4-dibenzyl-2-(difluoromethyl)piperazine 
• 934625-00-0 ethyl 1,4-dibenzyl-2-methylpiperazine-2-carboxylate 

Relevant articles and documents

TRICYCLIC PYRIDONES AND PYRIMIDONES

A compound of Formula (I) is provided: (I) where the variables are defined herein.

SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF

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QUINOLINE DERIVATIVES AS SMO INHIBITORS

Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.