sodiuM (E)-3-(3-Methoxy-4-((3,5,6-triMethylpyrazin-2-yl)Methoxy)phenyl)acrylate

Base Information

• Chemical Name: sodiuM (E)-3-(3-Methoxy-4-((3,5,6-triMethylpyrazin-2-yl)Methoxy)phenyl)acrylate
• CAS No.: 1018438-91-9
• Molecular Formula: C18H20N2O4
• Molecular Weight: 328.368
• Mol file: 1018438-91-9.mol

Synonyms:(E)-3-(4-((3,5,6-trimethylpyrazin-2-yl)methoxy)-3-methoxyphenyl)acrylic acid;

Chemical Property of sodiuM (E)-3-(3-Methoxy-4-((3,5,6-triMethylpyrazin-2-yl)Methoxy)phenyl)acrylate

Chemical Property:

• PSA: 81.54000
• LogP: 3.08720

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodiuM (E)-3-(3-Methoxy-4-((3,5,6-triMethylpyrazin-2-yl)Methoxy)phenyl)acrylate

There total 5 articles about sodiuM (E)-3-(3-Methoxy-4-((3,5,6-triMethylpyrazin-2-yl)Methoxy)phenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.6%

(E)-ethyl 3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylate (1018438-90-8) → (E)-3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylic acid (1018438-91-9)

Guidance literature:

(E)-ethyl 3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylate; With water; sodium hydroxide; In ethanol; at 20 ℃; for 4h;

With hydrogenchloride; In water; pH=4 - 5; Cooling;

Reference yield: 87.1%

(E)-(3,5,6-trimethylpyrazin-2-yl)methyl 3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylate → (E)-3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylic acid (1018438-91-9)

Guidance literature:

With ethanol; potassium hydroxide; at 60 ℃; for 0.5h;

Reference yield: 83.0%

C25H26N2O4 → (E)-3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylic acid (1018438-91-9)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 60 ℃; for 0.666667h;

DOI:10.1016/j.ejmech.2018.01.028

upstream raw materials:

(E)-ethyl 3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)phenyl)acrylate

ethyl 4-hydroxy-3-methoxycinnamate

benzyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate