3-Hydroxy-1-cyclohexene-1-carboxaldehyde

Base Information

Chemical Name:3-Hydroxy-1-cyclohexene-1-carboxaldehyde
CAS No.:67252-14-6
Molecular Formula:C7H10O2
Molecular Weight:126.1531
Hs Code.:
DSSTox Substance ID:DTXSID70455280
Nikkaji Number:J507.270K
Mol file:67252-14-6.mol

Synonyms:3-HYDROXY-1-CYCLOHEXENE-1-CARBOXALDEHYDE;3-hydroxy-1-cyclohexene-1-carbaldehyde;67252-14-6;SCHEMBL16321482;DTXSID70455280;3-hydroxy-cyclohexene-1-carbaldehyde

Suppliers and Price of 3-Hydroxy-1-cyclohexene-1-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Hydroxy-1-cyclohexene-1-carboxaldehyde

Chemical Property:

PSA：37.30000
LogP:0.65650
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:126.068079557
Heavy Atom Count:9
Complexity:138

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C=C(C1)C=O)O

Technology Process of 3-Hydroxy-1-cyclohexene-1-carboxaldehyde

There total 7 articles about 3-Hydroxy-1-cyclohexene-1-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 145788-36-9
Benzenesulfinic acid 3-formyl-cyclohex-2-enyl ester

: 67252-14-6
3-hydroxy-1-cyclohexene-1-carbaldehyde

Guidance literature:: With potassium hydroxide; In methanol; for 0.25h; Ambient temperature;
DOI:10.1246/bcsj.65.2966

Reference yield:

: 7205-94-9
chloromethyl phenyl sulfoxide

: 67252-14-6
3-hydroxy-1-cyclohexene-1-carbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) LDA / 1.) THF, -60 deg C, 10 min, 2.) THF, -60 deg C, 5 min

2: 62 percent / 2-methyl-propan-2-ol / 0.17 h / Ambient temperature

3: 83 percent / m-CPBA / CH₂Cl₂ / 0.17 h / 0 °C

4: 87 percent / 10percent aq. KOH / methanol / 0.25 h / Ambient temperature

With potassium hydroxide; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In methanol; dichloromethane; tert-butyl alcohol;
DOI:10.1246/bcsj.65.2966

Reference yield:

: 108139-15-7,145788-60-9
1-(phenylthio)-2-cyclohexene-1-carboxaldehyde

: 67252-14-6
3-hydroxy-1-cyclohexene-1-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / m-CPBA / CH₂Cl₂ / 0.17 h / 0 °C

2: 87 percent / 10percent aq. KOH / methanol / 0.25 h / Ambient temperature

With potassium hydroxide; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane;
DOI:10.1246/bcsj.65.2966