2-Chloro-5-ethylpyridine

Base Information

Chemical Name:2-Chloro-5-ethylpyridine
CAS No.:90196-32-0
Molecular Formula:C7H8ClN
Molecular Weight:141.6
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40456067
Wikidata:Q82278274
Mol file:90196-32-0.mol

Synonyms:2-Chloro-5-ethylpyridine;90196-32-0;2-chloro-5-ethyl-pyridine;Pyridine, 2-chloro-5-ethyl-;SCHEMBL91385;DTXSID40456067;HJQDSJJSRDWZIA-UHFFFAOYSA-N;MFCD18384612;AKOS015995134;SB23018;DS-14717;CS-0055009;FT-0664695;EN300-103017;A860885;J-508818

Suppliers and Price of 2-Chloro-5-ethylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-ethylpyridine
250mg
$ 165.00

J&W Pharmlab
2-Chloro-5-ethyl-pyridine 97%
500mg
$ 198.00

Crysdot
2-Chloro-5-ethylpyridine 98%
1g
$ 317.00

Chemenu
2-chloro-5-ethylpyridine 98%
1g
$ 299.00

American Custom Chemicals Corporation
2-CHLORO-5-ETHYLPYRIDINE 95.00%
5MG
$ 504.97

Ambeed
2-Chloro-5-ethylpyridine 96%
5g
$ 1047.00

Ambeed
2-Chloro-5-ethylpyridine 96%
250mg
$ 125.00

Ambeed
2-Chloro-5-ethylpyridine 96%
100mg
$ 78.00

Ambeed
2-Chloro-5-ethylpyridine 96%
1g
$ 321.00

Alichem
2-Chloro-5-ethylpyridine
250mg
$ 233.28

Total 22 raw suppliers

Chemical Property of 2-Chloro-5-ethylpyridine

Chemical Property:

Boiling Point:204.3±20.0 °C(Predicted)
PKA:0.50±0.10(Predicted)
PSA：12.89000
Density:1.111±0.06 g/cm3(Predicted)
LogP:2.29740
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:141.0345270
Heavy Atom Count:9
Complexity:85

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-ethylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CN=C(C=C1)Cl
Uses 2-Chloro-5-ethylpyridine is a disubstituted pyridine used in the preparation of biologically active compounds such as potential vanilloid receptor-1 antagonists.

Technology Process of 2-Chloro-5-ethylpyridine

There total 3 articles about 2-Chloro-5-ethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 157670-28-5
6-chloro-3-vinyl-pyridine

: 1121-55-7
3-vinylpyridine

: 536-78-7,151103-56-9
3-ethylpyridine

: 90196-32-0
2-chloro-5-ethyl-pyridine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; for 2h; under 760.051 Torr; Reagent/catalyst;

Reference yield:

: 23100-12-1
6-chloronicotinylaldehyde

: 1121-55-7
3-vinylpyridine

: 536-78-7,151103-56-9
3-ethylpyridine

: 90196-32-0
2-chloro-5-ethyl-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C

1.2: 2.5 h / 0 - 20 °C

2.1: hydrogen; palladium 10% on activated carbon / 2 h / 760.05 Torr

With palladium 10% on activated carbon; potassium tert-butylate; hydrogen; In tetrahydrofuran; 1.1: |Wittig Olefination;

Reference yield:

: 53939-30-3
5-bromo-2-chloropyridine

: 1121-55-7
3-vinylpyridine

: 536-78-7,151103-56-9
3-ethylpyridine

: 90196-32-0
2-chloro-5-ethyl-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 16 h / 84 °C / Inert atmosphere; Sealed tube

2: hydrogen; palladium 10% on activated carbon / 2 h / 760.05 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; sodium carbonate; In 1,2-dimethoxyethane; water; 1: |Suzuki Coupling;