1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone

Base Information

• Chemical Name: 1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone
• CAS No.: 153329-05-6
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• DSSTox Substance ID: DTXSID10601360
• Wikidata: Q82497970
• Mol file: 153329-05-6.mol

Synonyms:1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone;153329-05-6;1-[3-(1,3-DIOXOLAN-2-YL)PHENYL]ETHANONE;1-(3-(1,3-dioxolan-2-yl)phenyl)ethan-1-one;1-[3-(1,3-DIOXOLAN-2-YL)PHENYL]ETHAN-1-ONE;SCHEMBL4246223;DTXSID10601360;QFJWGOCXVSQXTM-UHFFFAOYSA-N;AB72909;DB-291227;G70679

Chemical Property of 1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 192.078644241
• Heavy Atom Count: 14
• Complexity: 209

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC=CC(=C1)C2OCCO2

Technology Process of 1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone

There total 2 articles about 1-(3-(1,3-Dioxolan-2-yl)phenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

acetic anhydride (108-24-7) → 1-(3-(1,3-dioxolan-2-yl)phenyl)ethanone (153329-05-6)

Guidance literature:

3-(1,3-dioxolan-2-yl)-phenylbromide; With iodine; magnesium; In tetrahydrofuran; at 20 - 40 ℃; for 2h;

acetic anhydride; In tetrahydrofuran; at -10 - 20 ℃; for 1h;

With water; sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield:

2-(furan-2-yl)-1,3-dioxolane (1708-41-4) + methyl vinyl ketone (78-94-4,25038-87-3) → 1-(3-(1,3-dioxolan-2-yl)phenyl)ethanone (153329-05-6) + (1,3-dioxolan-2-yl)phenylethanone (1256467-20-5)

Guidance literature:

2-(furan-2-yl)-1,3-dioxolane; methyl vinyl ketone; at 60 ℃; for 120h; Inert atmosphere;

With sodium t-butanolate; In dimethyl sulfoxide; at 30 ℃;

DOI:10.1002/cssc.202002111

upstream raw materials:

acetic anhydride

2-(furan-2-yl)-1,3-dioxolane

methyl vinyl ketone