(R)-2-benzylmorpholine

Base Information

Chemical Name:(R)-2-benzylmorpholine
CAS No.:131887-51-9
Molecular Formula:C₁₁H₁₅NO
Molecular Weight:177.246
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80439192
Nikkaji Number:J1.031.326K
Wikidata:Q82255098
Mol file:131887-51-9.mol

Synonyms:(R)-2-benzylmorpholine;131887-51-9;(2R)-2-BENZYLMORPHOLINE;(R)-2alpha-Benzylmorpholine;(2R)-2-(benzyl)morpholine;SCHEMBL1552999;DTXSID80439192;AMY21347;AKOS015904475;BS-49992;Morpholine, 2-(phenylmethyl)-, (2R)-;CS-0188089;E76215;EN300-8116377;A888356;J-500931;Z1255397150

Suppliers and Price of (R)-2-benzylmorpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(2R)-2-Benzylmorpholine
250 mg
$ 592.00

Crysdot
(R)-2-Benzylmorpholine 95%
1g
$ 772.00

Chemenu
(R)-2-Benzylmorpholine 95%
1g
$ 729.00

Apolloscientific
(2R)-2-Benzylmorpholine
250mg
$ 537.00

American Custom Chemicals Corporation
(R)-2-BENZYLMORPHOLINE 95.00%
100MG
$ 407.40

Alichem
(R)-2-Benzylmorpholine
1g
$ 671.96

Activate Scientific
(R)-2-Benzylmorpholine 95% ee
1 g
$ 923.00

ACHEMBLOCK
(R)-2-Benzylmorpholine 95%
1G
$ 450.00

Total 18 raw suppliers

Chemical Property of (R)-2-benzylmorpholine

Chemical Property:

Boiling Point:284.107 °C at 760 mmHg
PKA:8.97±0.40(Predicted)
Flash Point:112.288 °C
PSA：21.26000
Density:1.031 g/cm³
LogP:1.54630
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.115364102
Heavy Atom Count:13
Complexity:143

Purity/Quality:

97% ^*data from raw suppliers

(2R)-2-Benzylmorpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(CN1)CC2=CC=CC=C2
Isomeric SMILES:C1CO[C@@H](CN1)CC2=CC=CC=C2

Technology Process of (R)-2-benzylmorpholine

There total 8 articles about (R)-2-benzylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 300-57-2,57807-91-7
allylbenzene

: 87955-28-0,131887-48-4,131887-51-9,947687-18-5
(+)-2-benzylmorpholine

Guidance literature:: Multi-step reaction with 4 steps

1: NBS / H₂O / 48 h / 20 °C

2: aq. NaOH / 0.75 h / 65 °C

3: 1.) aq. NaOH, 2.) aq. NaOH / 1.) methanol, 2 h, 35-40 deg C, 2.) toluene, 65 deg C, 7.5 h

4: purification via salt with (+)-dibenzoyltartaric acid

With sodium hydroxide; N-Bromosuccinimide; In water;
DOI:10.1111/j.2042-7158.1990.tb07024.x

Reference yield:

: 300-57-2,57807-91-7
allylbenzene

: 87955-28-0,131887-48-4,131887-51-9,947687-18-5
(-)-2-benzylmorpholine

Guidance literature:: Multi-step reaction with 4 steps

1: NBS / H₂O / 48 h / 20 °C

2: aq. NaOH / 0.75 h / 65 °C

3: 1.) aq. NaOH, 2.) aq. NaOH / 1.) methanol, 2 h, 35-40 deg C, 2.) toluene, 65 deg C, 7.5 h

4: purification via salt with (-)-dibenzoyltartaric acid

With sodium hydroxide; N-Bromosuccinimide; In water;
DOI:10.1111/j.2042-7158.1990.tb07024.x

Reference yield:

: 4436-24-2
1,2-epoxy-3-phenylpropane

: 87955-28-0,131887-48-4,131887-51-9,947687-18-5
(+)-2-benzylmorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaOH, 2.) aq. NaOH / 1.) methanol, 2 h, 35-40 deg C, 2.) toluene, 65 deg C, 7.5 h

2: purification via salt with (+)-dibenzoyltartaric acid

With sodium hydroxide;
DOI:10.1111/j.2042-7158.1990.tb07024.x