3-Oxetaneacetic acid

Base Information

• Chemical Name: 3-Oxetaneacetic acid
• CAS No.: 1310381-54-4
• Molecular Formula: C₅H₈O₃
• Molecular Weight: 116.117
• Hs Code.: 2932999099
• Mol file: 1310381-54-4.mol

Synonyms:oxetan-3-ylacetic acid; 3-Oxetaneacetic Acid; 2-(Oxetan-3-yl)aceticacid

Chemical Property of 3-Oxetaneacetic acid

Chemical Property:

• Boiling Point: 260.1±13.0 °C(Predicted)
• PKA: 4.44±0.10(Predicted)
• PSA: 46.53000
• Density: 1.232±0.06 g/cm3(Predicted)
• LogP: 0.10750
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

2-(Oxetan-3-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Oxetaneacetic acid

There total 4 articles about 3-Oxetaneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.6%

benzyl 2-(oxetan-3-ylidene)acetate (1242160-03-7) → 2-(oxetan-3-yl) acetic acid (1310381-54-4)

Guidance literature:

With palladium on activated charcoal; hydrogen; In tetrahydrofuran; at 20 ℃; for 10h; Concentration;

Reference yield:

C7H12O3 → 2-(oxetan-3-yl) acetic acid (1310381-54-4)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

Reference yield:

ethyl 2-(oxetan-3-ylidene)acetate (922500-91-2) → 2-(oxetan-3-yl) acetic acid (1310381-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 1 h / 25 °C / 775.74 Torr

2: sodium hydroxide; water / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; water; hydrogen; sodium hydroxide; In tetrahydrofuran; ethanol;

upstream raw materials:

benzyl 2-(oxetan-3-ylidene)acetate

ethyl 2-(oxetan-3-ylidene)acetate