4-Amino-4'-methoxystilbene

Base Information

• Chemical Name: 4-Amino-4'-methoxystilbene
• CAS No.: 7570-37-8
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.29
• Hs Code.: 2922199090
• European Community (EC) Number: 691-451-8
• Nikkaji Number: J151.183A,J925.352A
• ChEMBL ID: CHEMBL3736179
• Mol file: 7570-37-8.mol

Synonyms:4-Amino-4'-methoxystilbene;7570-37-8;4-(4-Methoxystyryl)aniline;CCRIS 6784;4-[(E)-2-(4-methoxyphenyl)ethenyl]aniline;4'-Methoxy-4-stilbenamine;4-(2-(4-Methoxyphenyl)ethenyl)benzenamine;Benzenamine, 4-(2-(4-methoxyphenyl)ethenyl)-;SCHEMBL2588797;CHEMBL3736179;(E)-4'-Methoxystilben-4-amine;(E)-4-(4-methoxystyryl)aniline;MFCD00059856;AKOS015854903;LS-28360;A0326;CS-0331136;T71306;(E)-4-[2-(4-methoxy-phenyl)-vinyl]-phenylamine;SR-01000392128;4-[(E)-2-(4-Methoxyphenyl)ethenyl]phenylamine #;SR-01000392128-1

Chemical Property of 4-Amino-4'-methoxystilbene

Chemical Property:

• Melting Point: 173 °C
• Boiling Point: 412.4 °C at 760 mmHg
• Flash Point: 215.4 °C
• PSA: 35.25000
• Density: 1.132 g/cm³
• LogP: 4.02900
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 225.115364102
• Heavy Atom Count: 17
• Complexity: 235

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Amino-4''-methoxystilbene ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=CC2=CC=C(C=C2)N
• Isomeric SMILES: COC1=CC=C(C=C1)/C=C/C2=CC=C(C=C2)N

Technology Process of 4-Amino-4'-methoxystilbene

There total 5 articles about 4-Amino-4'-methoxystilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

→ 4-amino-4'-methoxystilbene (7314-07-0,7570-37-8)

Guidance literature:

Reference yield: 59.0%

1-methoxy-4-[2-(4-nitrophenyl)ethenyl]benzene (1472-68-0,4648-14-0,4648-33-3) → 4-amino-4'-methoxystilbene (7314-07-0,7570-37-8)

Guidance literature:

With tin(II) chloride dihdyrate; In ethanol; for 24h; Inert atmosphere; Reflux;

DOI:10.1002/cphc.201100885

Reference yield:

4-nitrobenzeneacetic acid (104-03-0) → 4-amino-4'-methoxystilbene (7314-07-0,7570-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine / 130 °C

2: tin dichloride; glacial acetic acid-hydrogen chloride

With piperidine; hydrogenchloride; acetic acid; tin(ll) chloride;

upstream raw materials:

1-methoxy-4-[2-(4-nitrophenyl)ethenyl]benzene

4-nitrobenzeneacetic acid

4-methoxy-benzaldehyde

Downstream raw materials:

2-[(4'-methoxyldiphenylethylene-4-ylimino)methyl]phenol

4-[(4'-methoxyldiphenylethylene-4-ylimino)methyl]phenol

Refernces

• 1、 -. "N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS". Page 36. . Retrieved 2008/06/13.