1-Isobutylpiperidin-4-amine

Base Information

Chemical Name:1-Isobutylpiperidin-4-amine
CAS No.:42450-36-2
Molecular Formula:C9H20N2
Molecular Weight:156.271
Hs Code.:2933399090
European Community (EC) Number:809-460-4
DSSTox Substance ID:DTXSID40338713
Wikidata:Q82107299
ChEMBL ID:CHEMBL4548063
Mol file:42450-36-2.mol

Synonyms:1-isobutylpiperidin-4-amine;42450-36-2;1-(2-methylpropyl)piperidin-4-amine;1-ISOBUTYL-PIPERIDIN-4-YLAMINE;4-Amino-1-isobutylpiperidine;1-Isobutyl-4-piperidinamine #;SCHEMBL3960904;CHEMBL4548063;DTXSID40338713;MFCD03411604;STK351555;AKOS005167510;SB37150;BS-13421;1-Isobutyl-piperidin-4-ylamine, AldrichCPR;CS-0215865;FT-0709912;EN300-30377;J-503050

Suppliers and Price of 1-Isobutylpiperidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-isobutylpiperidin-4-amine
500mg
$ 285.00

TRC
1-isobutylpiperidin-4-amine
50mg
$ 45.00

J&W Pharmlab
1-Isobutyl-piperidin-4-ylamine 96%
500mg
$ 149.00

Crysdot
1-Isobutylpiperidin-4-amine 95+%
1g
$ 299.00

Chemenu
1-isobutylpiperidin-4-amine 95%
1g
$ 282.00

American Custom Chemicals Corporation
1-(2-METHYLPROPYL)PIPERIDIN-4-AMINE 95.00%
5G
$ 1295.03

American Custom Chemicals Corporation
1-(2-METHYLPROPYL)PIPERIDIN-4-AMINE 95.00%
2.5G
$ 1065.66

American Custom Chemicals Corporation
1-(2-METHYLPROPYL)PIPERIDIN-4-AMINE 95.00%
1G
$ 765.23

Alichem
1-Isobutylpiperidin-4-amine
1g
$ 400.00

AK Scientific
1-Isobutylpiperidin-4-amine
500mg
$ 376.00

Total 19 raw suppliers

Chemical Property of 1-Isobutylpiperidin-4-amine

Chemical Property:

Vapor Pressure:0.573mmHg at 25°C
Boiling Point:81.5-82.5℃ (11.5 Torr)
Flash Point:68.8°C
PSA：29.26000
Density:0.887g/cm³
LogP:1.70370
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:156.162648646
Heavy Atom Count:11
Complexity:104

Purity/Quality:

97% ^*data from raw suppliers

1-isobutylpiperidin-4-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CN1CCC(CC1)N

Technology Process of 1-Isobutylpiperidin-4-amine

There total 1 articles about 1-Isobutylpiperidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 182223-54-7
piperidin-4-ylcarbamic acid benzyl ester

: 42450-36-2
1-(2-methylpropyl)piperidin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 5 h / Reflux

2: hydrogen; palladium 10% on activated carbon / 20 h / 20 °C / 760.05 Torr

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; In acetonitrile;
DOI:10.1016/j.ejmech.2017.03.013

Reference yield: 52.0%

: 42450-36-2
1-(2-methylpropyl)piperidin-4-amine

: 4659-45-4
2,6-Dichlorobenzoyl chloride

: 2,6-dichloro-N-(1-isobutylpiperidin-4-yl)benzamide

Guidance literature:: In 1,4-dioxane; at 20 ℃; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b01900

Reference yield: 39.0%

: 42450-36-2
1-(2-methylpropyl)piperidin-4-amine

: ethyl 2-(1-((1r,4r)-4-(cyanomethyl)cyclohexyl)-6-(phenylsulfonyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)acetate

: 2-(1-((1r,4r)-4-(cyanomethyl)cyclohexyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-N-(1-isobutylpiperidin-4-yl)acetamide

Guidance literature:: 1-(2-methylpropyl)piperidin-4-amine; ethyl 2-(1-((1r,4r)-4-(cyanomethyl)cyclohexyl)-6-(phenylsulfonyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)acetate; at 125 ℃; for 22h; Microwave irradiation;

With potassium hydroxide; In 1,4-dioxane; at 20 - 80 ℃; for 2h; Microwave irradiation;