3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid

Base Information

Chemical Name:3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid
CAS No.:206537-28-2
Molecular Formula:C14H18N2O6
Molecular Weight:310.3
Hs Code.:
DSSTox Substance ID:DTXSID40426008
Mol file:206537-28-2.mol

Synonyms:206537-28-2;3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid;3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2-nitrophenyl)propanoic Acid;3-(N-BOC)AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID;3-(Tert-butoxycarbonylamino)-3-(2-nitrophenyl)propanoic acid;3-[(tert-butoxycarbonyl)amino]-3-(2-nitrophenyl)propanoic acid;Boc-3-Amino-3-(2-nitrophenyl)propionic acid;DTXSID40426008;MFCD02090716;WS-00643;3-(t-Butoxycarbonylamino)-3-(2-nitrophenyl)propanoic acid;3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoicacid;Benzenepropanoic acid, |A-[[(1,1-dimethylethoxy)carbonyl]amino]-2-nitro-;Benzenepropanoic acid, beta-[[(1,1-dimethylethoxy)carbonyl]amino]-2-nitro-

Suppliers and Price of 3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoicacid 97%
1g
$ 490.00

American Custom Chemicals Corporation
3-(N-BOC)AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID 95.00%
5MG
$ 497.24

Acrotein
Boc-3-Amino-3-(2-nitrophenyl)propionicacid 97%
5g
$ 495.00

Aaron Chemicals
Benzenepropanoicacid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-2-nitro- 95%
250mg
$ 66.00

Aaron Chemicals
Benzenepropanoicacid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-2-nitro- 95%
100mg
$ 40.00

Total 8 raw suppliers

Chemical Property of 3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid

Chemical Property:

Vapor Pressure:2.44E-11mmHg at 25°C
Boiling Point:512.8°C at 760 mmHg
Flash Point:263.9°C
PSA：121.45000
Density:1.288g/cm³
LogP:3.54940
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:310.11648630
Heavy Atom Count:22
Complexity:426

Purity/Quality:

98% ^*data from raw suppliers

3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC(=O)O)C1=CC=CC=C1[N+](=O)[O-]

Technology Process of 3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid

There total 1 articles about 3-((tert-Butoxycarbonyl)amino)-3-(2-nitrophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 5678-48-8,732242-02-3,756814-14-9
3-amino-3-(2-nitrophenyl)propionic acid

: 206537-28-2,500770-83-2,501015-23-2
3-N^α-tBoc-amino-3-(2-nitrophenyl)propionic acid

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In methanol; at 20 ℃; for 0.333333h;
DOI:10.1021/ja035360b

Reference yield: 73.0%

: 391624-46-7
9-fluorenylmethyl N-(2-aminoethyl)carbamate hydrochloride

: 206537-28-2,500770-83-2,501015-23-2
3-N^α-tBoc-amino-3-(2-nitrophenyl)propionic acid

: N¹-[2-(9-fluorenylmethoxycarbonyl)ethyl]-3-[(tert-butoxycarbonyl)amino]-3-(2-nitrophenyl)propionamide

Guidance literature:: With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/anie.201201627

Reference yield:

: 206537-28-2,500770-83-2,501015-23-2
3-N^α-tBoc-amino-3-(2-nitrophenyl)propionic acid

: N¹-[2-(9-fluorenylmethoxycarbonyl)ethyl]-3-amino-3-(2-nitrophenyl)propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: BOP / dimethylformamide / 0.08 h

2: DIEPA / dimethylformamide / 20 °C

3: 94 percent / TFA / CH₂Cl₂ / 0.67 h / 0 - 20 °C

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja035360b