4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine

Base Information

Chemical Name:4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine
CAS No.:957198-30-0
Molecular Formula:C14H22BN3O3
Molecular Weight:291.158
Hs Code.:2934999090
European Community (EC) Number:894-071-2
DSSTox Substance ID:DTXSID50585958
Wikidata:Q72493025
Mol file:957198-30-0.mol

Synonyms:957198-30-0;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine;4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]morpholine;C14H22BN3O3;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID, PINACOL ESER;MFCD07368246;4-(5-(4455-Tetramethyl-132-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine;SCHEMBL1877437;DTXSID50585958;HNVAYPJNFUXYII-UHFFFAOYSA-N;(2-MORPHOLINOPYRIMIDIN-5-YL)BORONIC ACID PINACOL ESTER;MFCD17167301;AKOS005259718;AB31990;CS-W019234;AC-33451;AM804614;DS-14810;SY066330;EN300-7386095;2-Morpholinopyrimidine-5-boronic Acid Pinacol Ester;2-(4-Thiomorpholino)pyrimidine-5-boronic acid, pinacol ester;2-(MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester, AldrichCPR;4-[5-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDIN-2-YL]MORPHOLINE

Suppliers and Price of 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester
500mg
$ 496.00

TRC
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
50mg
$ 45.00

TRC
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
100mg
$ 60.00

Sigma-Aldrich
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester Aldrich
1g
$ 258.00

Matrix Scientific
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester 95+%
5g
$ 585.00

Matrix Scientific
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester 95+%
1g
$ 175.00

Crysdot
4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine 97%
5g
$ 413.00

Crysdot
4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine 97%
1g
$ 103.00

AOBChem
2-(4-Morpholino)pyrimidine-5-boronicacid,pinacoleser 95%
100g
$ 2695.00

AOBChem
2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol eser 97%
50g
$ 1686.00

Total 41 raw suppliers

Chemical Property of 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine

Chemical Property:

Boiling Point:453.4 °C at 760 mmHg
Flash Point:228 °C
PSA：56.71000
Density:1.16 g/cm³
LogP:0.67740
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:291.1754217
Heavy Atom Count:21
Complexity:351

Purity/Quality:

99%, ^*data from raw suppliers

2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CN=C(N=C2)N3CCOCC3

Technology Process of 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine

There total 2 articles about 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 84539-22-0
4-(5-bromopyrimidin-2-yl)morpholine

: 73183-34-3
bis(pinacol)diborane

: 957198-30-0
4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]morpholine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 90 ℃; Inert atmosphere;

Reference yield:

: 957198-30-0
4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]morpholine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 100 ℃; for 4.5h;

Reference yield: 100.0%

: 957198-30-0
4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]morpholine

: trans-1-(4-bromo-5-fluoro-2-nitrophenyl)-4-methoxy-N-(2-methoxyethyl)-N-methylpyrrolidin-3-amine

: trans-1-(5-fluoro-4-(2-morpholinopyrimidin-5-yl)-2-nitrophenyl)-4-methoxy-N-(2-methoxyethyl)-N-methylpyrrolidin-3-amine

Guidance literature:: With potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); In 1,4-dioxane; water; at 110 ℃; for 0.666667h; Inert atmosphere; Microwave irradiation;