2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid

Base Information

Chemical Name:2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid
CAS No.:81745-21-3
Molecular Formula:C11H11NO3
Molecular Weight:205.21
Hs Code.:2933499090
European Community (EC) Number:820-570-1
DSSTox Substance ID:DTXSID00588439
Nikkaji Number:J3.592.083H
Wikidata:Q82481106
Mol file:81745-21-3.mol

Synonyms:81745-21-3;2-(2-OXO-3,4-DIHYDROQUINOLIN-1(2H)-YL)ACETIC ACID;(2-Oxo-3,4-dihydro-2H-quinolin-1-yl)-acetic acid;2-(2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetic acid;2-(2-oxo-3,4-dihydroquinolin-1-yl)acetic acid;(2-OXO-3,4-DIHYDROQUINOLIN-1-YL)ACETIC ACID;SCHEMBL933584;DTXSID00588439;LQGIKCCIECNYHT-UHFFFAOYSA-N;MFCD09730955;AKOS000142151;MCULE-6275747202;AS-67935;DB-013886;CS-0084235;EN300-74253;F52057;(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid;Z271097322;2-(2-OXO-3,4-DIHYDROQUINOLIN-1(2H)-YL)ACETICACID

Suppliers and Price of 2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dihydro-2-oxo-1(2H)-quinolineaceticAcid
25mg
$ 65.00

Crysdot
2-(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)aceticacid 95+%
5g
$ 629.00

Chemenu
2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)aceticacid 95%
5g
$ 594.00

American Custom Chemicals Corporation
2-(2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-1-YL)ACETIC ACID 95.00%
5MG
$ 502.55

Alichem
2-(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)aceticacid
5g
$ 501.76

Alichem
2-(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)aceticacid
1g
$ 170.28

AK Scientific
2-(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)aceticacid
10g
$ 3032.00

Total 10 raw suppliers

Chemical Property of 2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid

Chemical Property:

Boiling Point:507.6±50.0 °C(Predicted)
PKA:3.71±0.10(Predicted)
PSA：57.61000
Density:1.315±0.06 g/cm3(Predicted)
LogP:1.11540
Storage Temp.:2-8°C
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:277

Purity/Quality:

99.3% ^*data from raw suppliers

3,4-Dihydro-2-oxo-1(2H)-quinolineaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C2=CC=CC=C21)CC(=O)O

Technology Process of 2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid

There total 6 articles about 2-(2-Oxo-3,4-dihydroquinolin-1(2H)-YL)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: C₁₃H₁₆N₂O₂

: 81745-21-3
2-(2- oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; methanol; at 80 ℃; for 24h; Sealed tube;
DOI:10.1039/c6cc02865a

Reference yield: 77.0%

: 553-03-7
3,4-dihydro-2(1H)-quinolone

: 105-36-2
ethyl bromoacetate

: 81745-21-3
2-(2- oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid

Guidance literature:: 3,4-dihydro-2(1H)-quinolone; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

ethyl bromoacetate; In N,N-dimethyl-formamide; Inert atmosphere;

With lithium hydroxide; In tetrahydrofuran; water; for 5h; Inert atmosphere;
DOI:10.1021/acs.orglett.9b04587

Reference yield:

: (2-oxo-3,4-dihydro-2H-quinolin-1-yl)-acetic acid ethyl ester

: 81745-21-3
2-(2- oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid

Guidance literature:: (2-oxo-3,4-dihydro-2H-quinolin-1-yl)-acetic acid ethyl ester; With sodium hydroxide; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In water; pH=1;