7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Base Information

Chemical Name:7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS No.:917748-98-2
Molecular Formula:C15H14N2O2
Molecular Weight:254.288
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30594442
Wikidata:Q82489271
Mol file:917748-98-2.mol

Synonyms:917748-98-2;7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one;7-amino-4-benzyl-1,4-benzoxazin-3-one;7-amino-4-benzyl-3,4-dihydro-2H-1,4-benzoxazin-3-one;7-Amino-4-benzyl-4H-benzo[1,4]oxazin-3-one;7-Amino-4-benzyl-2H-1,4-benzoxazin-3(4H)-one;SCHEMBL758149;DTXSID30594442;AKOS000676671;DB-014666;CS-0348946;EN300-1107356

Suppliers and Price of 7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one 95+%
1g
$ 510.00

Chemenu
7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one 95%
1g
$ 482.00

American Custom Chemicals Corporation
7-AMINO-4-BENZYL-2H-1,4-BENZOXAZIN-3(4H)-ONE 95.00%
1G
$ 1172.13

Alichem
7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one
1g
$ 407.68

Total 5 raw suppliers

Chemical Property of 7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Chemical Property:

PSA：55.56000
LogP:2.84060
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:254.105527694
Heavy Atom Count:19
Complexity:328

Purity/Quality:

99% ^*data from raw suppliers

7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C2=C(O1)C=C(C=C2)N)CC3=CC=CC=C3

Technology Process of 7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

There total 7 articles about 7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 917748-98-2
7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Guidance literature:: 7-amino-2H-1,4-benzoxazin-3(4H)-one; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.25h;

benzyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

Reference yield:

: tert-butyl (4-benzyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)carbamate

: 917748-98-2
7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

: 142166-00-5
methyl 3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylate

: 917748-98-2
7-amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

2.1: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 124 h / 20 °C

3.1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 1 h / 0 - 20 °C

3.2: 1 h / 20 °C

4.1: 1 h / 90 °C

5.1: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C / Inert atmosphere

With hydrogenchloride; oxalyl dichloride; lithium hydroxide monohydrate; water; sodium hydride; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;