4,6,7-trihydroxycoumarin

Base Information

• Chemical Name: 4,6,7-trihydroxycoumarin
• CAS No.: 22649-24-7
• Molecular Formula: C9H6O5
• Molecular Weight: 194.14100
• Mol file: 22649-24-7.mol

Synonyms:4,6,7-trihydroxycoumarin;;4,6,7-Trihydroxy-cumarin;;4,6,7-trihydroxy-coumarin;;4,6,7-Trihydroxy-chromen-2-one;;

Chemical Property of 4,6,7-trihydroxycoumarin

Chemical Property:

• PSA: 90.90000
• LogP: 0.90980

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6,7-trihydroxycoumarin

There total 2 articles about 4,6,7-trihydroxycoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,4-Trihydroxybenzene (533-73-3) + ethyl 2-cyanoacetate (105-56-6) → 4,6,7-Trihydroxy-cumarin (22649-24-7)

Guidance literature:

With diethyl ether; zinc(II) chloride; Einleiten von Chlorwasserstoff und Erhitzen des Reaktionsprodukts mit wss. Schwefelsaeure;

Reference yield:

→ 4,6,7-Trihydroxy-cumarin (22649-24-7)

Guidance literature:

aus 1-(2,4,5,Trihydroxy-pheny)-aethanon;

DOI:10.1021/jm00284a022

upstream raw materials:

1,2,4-Trihydroxybenzene

ethyl 2-cyanoacetate