3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

Base Information

Chemical Name:3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
CAS No.:1111637-91-2
Molecular Formula:C12H19BN2O2
Molecular Weight:234.106
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40681918
Wikidata:Q82606098
Mol file:1111637-91-2.mol

Synonyms:1111637-91-2;3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine;2-Amino-3-methylpyridine-5-boronic acid pinacol ester;(6-AMINO-5-METHYLPYRIDIN-3-YL)BORONIC ACID PINACOL ESTER;SCHEMBL2271569;DTXSID40681918;BWEOUBYDXFBFMA-UHFFFAOYSA-N;MFCD12923388;AKOS016001326;MB12122;AS-36250;CS-0136096;FT-0768320;J-512862;3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-amine

Suppliers and Price of 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 22 raw suppliers

Chemical Property of 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

Chemical Property:

PSA：57.37000
LogP:1.85260
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:234.1539580
Heavy Atom Count:17
Complexity:280

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(N=C2)N)C

Technology Process of 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

There total 1 articles about 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3430-21-5
5-bromo-3-methyl-pyridin-2-ylamine

: 73183-34-3
bis(pinacol)diborane

: 1111637-91-2
3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

Guidance literature:: With potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 80 - 90 ℃;

Reference yield: 58.0%

: 1111637-91-2
3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

: ethyl 2-(3-(4-(8-bromo-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)oxetan-3-yl)acetate

: ethyl 2-(3-(4-(8-(6-amino-5-methylpyridin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)oxetan-3-yl)acetate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In water; N,N-dimethyl-formamide; at 111 ℃; for 0.1h; Microwave irradiation;

Reference yield:

: 1111637-91-2
3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

: 3-(5-amino-3-iodo-pyrazolo[1,5-a]pyrimidin-2-yl)benzonitrile

: 3-[5-amino-3-(6-amino-5-methyl-3-pyridyl)pyrazolo[1,5-a]pyrimidin-2-yl]benzonitrile

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 80 ℃; for 2.25h; Inert atmosphere;