N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine

Base Information

• Chemical Name: N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine
• CAS No.: 1289386-31-7
• Molecular Formula: C₈H₁₀ClN₃
• Molecular Weight: 183.64
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID60693775
• Wikidata: Q72518172
• Mol file: 1289386-31-7.mol

Synonyms:1289386-31-7;N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine;(2-Chloro-pyrimidin-4-ylmethyl)-cyclopropyl-amine;N-[(2-chloropyrimidin-4-yl)methyl]cyclopropanamine;SCHEMBL17601073;DTXSID60693775;XEJWSLRUNWUNGQ-UHFFFAOYSA-N;AKOS015940278;AM91567;SB56114;(2-Chloro-pyrimidin-4-ylmethyl)cyclopropylamine

Chemical Property of N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine

Chemical Property:

• Boiling Point: 338.8±17.0 °C(Predicted)
• PKA: 6.45±0.20(Predicted)
• PSA: 37.81000
• Density: 1.29
• LogP: 1.77290
• Storage Temp.: 2-8°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 183.0563250
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

98% ^*data from raw suppliers

N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NCC2=NC(=NC=C2)Cl

Technology Process of N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine

There total 1 articles about N-((2-Chloropyrimidin-4-yl)methyl)cyclopropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

2-chloro-4-pyrimidinylmethyl chloride (944902-31-2) + Cyclopropylamine (765-30-0) → N-((2-chloropyrimidin-4-yl)methyl)cyclopropanamine (1289386-31-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

upstream raw materials:

2-chloro-4-pyrimidinylmethyl chloride

Cyclopropylamine