Chemical Property of Picamilon
Chemical Property:
- Appearance/Colour:white crystalline powder
- Vapor Pressure:9.65E-12mmHg at 25°C
- Melting Point:210-212oC
- Boiling Point:522.4 °C at 760 mmHg
- PKA:4.60±0.10(Predicted)
- Flash Point:269.8 °C
- PSA：79.29000
- Density:1.245 g/cm3
- LogP:1.06710
- Storage Temp.:Inert atmosphere,Room Temperature
- Solubility.:DMSO (Slightly, Heated), Methanol (Slightly)
- XLogP3:-0.4
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:5
- Exact Mass:208.08479225
- Heavy Atom Count:15
- Complexity:231
- Purity/Quality:
-
99% *data from raw suppliers
Nicotinoyl-γ-aminobutyricAcid *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC(=CN=C1)C(=O)NCCCC(=O)O
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Description
Pikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.
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Clinical Use
Pikamilone treatment of benign prostatic hyperplasiaPikamilone is an original drug of Russian produce having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action. The drug was tried as monotherapy in elderly patients with benign prostatic hyperplasia who had symptoms of the lower urinary tracts to estimate its effect on local and general mechanisms of nervous and vascular regulation of detruzor function in infravesical obstruction. https://pubmed.ncbi.nlm.nih.gov/11150159/
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Uses
Nicotinoyl-γ-aminobutyric Acid is a pro-drug of γ-Aminobutyric Acid (A602920). Studies show that Nicotinoyl-γ-aminobutyric Acid is involved in the regulation of the processes in the brain of streptozotocin-induced diabetic rats.
