(R)-4-Chlorobenzhydrol

Base Information

Chemical Name:(R)-4-Chlorobenzhydrol
CAS No.:123535-85-3
Molecular Formula:C13H11ClO
Molecular Weight:218.683
Hs Code.:
European Community (EC) Number:204-333-4
UNII:PA8COP3FYC
Nikkaji Number:J595.877F
Wikidata:Q27286438
ChEMBL ID:CHEMBL2251570
Mol file:123535-85-3.mol

Synonyms:(R)-4-Chlorobenzhydrol;4-Chlorobenzhydrol, (R)-;(-)-4-Chlorobenzhydrol;4-Chlorobenzhydrol, (-)-;123535-85-3;(R)-(4-chlorophenyl)-phenylmethanol;PA8COP3FYC;UNII-PA8COP3FYC;(alphaR)-4-Chloro-alpha-phenylbenzenemethanol;(R)-4-Chlorophenyl benzenemethanol;Benzenemethanol, 4-chloro-alpha-phenyl-, (alphaR)-;4-Chlorobenzhydryl alcohol;SCHEMBL477349;CHEMBL2251570;(R)-(4-chlorophenyl)-phenyl-methanol;(R)-(4-Chlorophenyl)(phenyl)methanol;A804316;Q27286438;(.ALPHA.R)-4-CHLORO-.ALPHA.-PHENYLBENZENEMETHANOL;BENZENEMETHANOL, 4-CHLORO-.ALPHA.-PHENYL-, (.ALPHA.R)-

Suppliers and Price of (R)-4-Chlorobenzhydrol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (R)-4-Chlorobenzhydrol

Chemical Property:

PSA：20.23000
LogP:3.42170
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:218.0498427
Heavy Atom Count:15
Complexity:181

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)O
Isomeric SMILES:C1=CC=C(C=C1)[C@H](C2=CC=C(C=C2)Cl)O

Technology Process of (R)-4-Chlorobenzhydrol

There total 60 articles about (R)-4-Chlorobenzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 104-88-1
4-chlorobenzaldehyde

: 98-80-6
phenylboronic acid

: 123535-85-3
(R)-(4-chlorophenyl)phenylmethanol

Guidance literature:: phenylboronic acid; With diethylzinc; In toluene; at 50 ℃; for 10h; Inert atmosphere;

With Thioacetic acid S-((1R,2S)-1-phenyl-2-piperidin-1-yl-propyl) ester; In toluene; at 20 ℃; for 0.333333h; Inert atmosphere;

4-chlorobenzaldehyde; In toluene; at 10 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol8001249

Reference yield: 96.0%

: 104-88-1
4-chlorobenzaldehyde

: 100-58-3
phenylmagnesium bromide

: 123535-85-3
(R)-(4-chlorophenyl)phenylmethanol

Guidance literature:: phenylmagnesium bromide; With titanium(IV) isopropylate; In dichloromethane; at -78 ℃; for 0.166667h; Inert atmosphere;

4-chlorobenzaldehyde; With (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; In diethyl ether; dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

With hydrogenchloride; water; In diethyl ether; dichloromethane; at 0 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1246/bcsj.20090232