2-(ethylamino)isonicotinonitrile

Base Information

Chemical Name:2-(ethylamino)isonicotinonitrile
CAS No.:87121-58-2
Molecular Formula:C₈H₉N₃
Molecular Weight:147.18
Hs Code.:2933399090
Mol file:87121-58-2.mol

Synonyms:2-(Ethylamino)-4-pyridinecarbonitrile;2-(ethylamino)isonicotinonitrile;2-N-ethylaminoisonicotinonitrile;

Suppliers and Price of 2-(ethylamino)isonicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(Ethylamino)isonicotinonitrile 95+%
1g
$ 377.00

Chemenu
2-(ethylamino)isonicotinonitrile 95%
1g
$ 356.00

American Custom Chemicals Corporation
2-(ETHYLAMINO)-4-PYRIDINECARBONITRILE 95.00%
5MG
$ 504.50

Alichem
2-(Ethylamino)isonicotinonitrile
1g
$ 400.00

Total 12 raw suppliers

Chemical Property of 2-(ethylamino)isonicotinonitrile

Chemical Property:

Boiling Point:276℃
Flash Point:121℃
PSA：51.94000
Density:1.10
LogP:0.80698
Storage Temp.:2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

2-(Ethylamino)isonicotinonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(ethylamino)isonicotinonitrile

There total 2 articles about 2-(ethylamino)isonicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.7%

: 33252-30-1
2-chloro-4-pyridinenitrile

: 75-04-7,85404-22-4
ethylamine

: 87121-58-2
2-N-ethylaminoisonicotinonitrile

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1,2-dimethoxyethane; at 120 ℃; for 2h; Microwave irradiation;
DOI:10.1021/jm500833f

Reference yield: 12.0%

: 33252-30-1
2-chloro-4-pyridinenitrile

: 75-04-7,85404-22-4
ethylamine

: 87121-58-2
2-N-ethylaminoisonicotinonitrile

: 87121-59-3
2-Chloro-N,N'-diethyl-isonicotinamidine

Guidance literature:: In tetrahydrofuran; toluene; at 150 ℃; for 4h; high pressure;

Reference yield:

: 87121-58-2
2-N-ethylaminoisonicotinonitrile

: N-(2-ethylamino-pyridin-4-ylmethyl)-6-[4-(3-fluoro-benzyloxy)-phenoxy]-nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / ammonia; Raney Ni; H₂ / methanol; H₂O / 3 h / 20 °C / 2500.73 Torr

2: 74 percent / 1-hydroxybenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride / dimethylformamide / 20 °C

With ammonia; hydrogen; nickel; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.03.052