2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one

Base Information

Chemical Name:2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one
CAS No.:125159-93-5
Molecular Formula:C₁₆H₁₅NO₃S
Molecular Weight:301.366
Hs Code.:
Mol file:125159-93-5.mol

Synonyms:2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one;2-(4-methylphenyl)sulfonyl-1,3-dihydroisoquinolin-4-one;4(1H)-Isoquinolinone, 2,3-dihydro-2-[(4-methylphenyl)sulfonyl]-

Suppliers and Price of 2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-tosyl-2,3-dihydroisoquinolin-4(1H)-one 95
25g
$ 1000.00

Labseeker
2-tosyl-2,3-dihydroisoquinolin-4(1H)-one 95
10g
$ 917.00

Labseeker
2-tosyl-2,3-dihydroisoquinolin-4(1H)-one 95
5g
$ 633.00

Total 5 raw suppliers

Chemical Property of 2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one

Chemical Property:

PSA：62.83000
LogP:3.40090

Purity/Quality:

98%min ^*data from raw suppliers

2-tosyl-2,3-dihydroisoquinolin-4(1H)-one 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one

There total 4 articles about 2 - tosyl - 2,3 - dihydroisoquinolin - 4(1H) - one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 125159-94-6
N-tosyl-N-benzyl-aminoacetyl chloride

: 125159-93-5
2-tosyl-1,2,3,4-tetrahydro-4-isoquinolone

Guidance literature:: With aluminium trichloride; In dichloromethane; at 20 ℃; for 1h; Yield given;

Reference yield:

: 20158-69-4
2-(N-benzyl-4-methylphenylsulfonamido)acetic acid

: 125159-93-5
2-tosyl-1,2,3,4-tetrahydro-4-isoquinolone

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / Heating

2: AlCl₃ / CH₂Cl₂ / 1 h / 20 °C

With aluminium trichloride; thionyl chloride; In dichloromethane;

Reference yield:

: 2645-02-5
methyl tosylglycinate

: 125159-93-5
2-tosyl-1,2,3,4-tetrahydro-4-isoquinolone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) K₂CO₃, NaI, 2.) 10percent aq. NaOH / 1.) acetone, reflux, 6 h, 2.) 50 deg C, 4 h

2: SOCl₂ / Heating

3: AlCl₃ / CH₂Cl₂ / 1 h / 20 °C

With sodium hydroxide; aluminium trichloride; thionyl chloride; potassium carbonate; sodium iodide; In dichloromethane;