4-Chloro-2-phenylthieno[3,2-d]pyrimidine

Base Information

Chemical Name:4-Chloro-2-phenylthieno[3,2-d]pyrimidine
CAS No.:214417-22-8
Molecular Formula:C12H7ClN2S
Molecular Weight:246.72
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60363325
Nikkaji Number:J2.799.117C
Wikidata:Q82146976
Mol file:214417-22-8.mol

Synonyms:4-chloro-2-phenylthieno[3,2-d]pyrimidine;214417-22-8;HMS1367G04;Bionet2_001192;SCHEMBL4744102;DTXSID60363325;AKOS005100491;2-Phenyl-4-chlorothieno[3,2-d]pyrimidine;CS-0328322;FT-0721921;A23826;7R-1316

Suppliers and Price of 4-Chloro-2-phenylthieno[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-2-phenylthieno[3,2-d]pyrimidine 95+%
1g
$ 353.00

Chemenu
4-chloro-2-phenylthieno[3,2-d]pyrimidine 95%
1g
$ 333.00

American Custom Chemicals Corporation
4-CHLORO-2-PHENYLTHIENO[3,2-D]PYRIMIDINE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
4-CHLORO-2-PHENYLTHIENO[3,2-D]PYRIMIDINE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
4-CHLORO-2-PHENYLTHIENO[3,2-D]PYRIMIDINE 95.00%
1MG
$ 647.61

Alichem
4-Chloro-2-phenylthieno[3,2-d]pyrimidine
1g
$ 400.00

Total 10 raw suppliers

Chemical Property of 4-Chloro-2-phenylthieno[3,2-d]pyrimidine

Chemical Property:

Melting Point:118-119 °C
Boiling Point:299.1±22.0 °C(Predicted)
PKA:0.38±0.40(Predicted)
PSA：54.02000
Density:1.396±0.06 g/cm3(Predicted)
LogP:4.01170
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:246.0018471
Heavy Atom Count:16
Complexity:245

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-phenylthieno[3,2-d]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=C(C(=N2)Cl)SC=C3

Technology Process of 4-Chloro-2-phenylthieno[3,2-d]pyrimidine

There total 3 articles about 4-Chloro-2-phenylthieno[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 18678-14-3
2-phenyl-3H-thieno[3,2-d]pyrimidin-4-one

: 214417-22-8
4-chloro-2-phenylthieno[3,2-d]pyrimidine

Guidance literature:: With trichlorophosphate; for 4h; Reflux;
DOI:10.1039/b915274a

Reference yield:

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 214417-22-8
4-chloro-2-phenylthieno[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) pyridine, 2.) 30percent NH₃ / 1.) CHCl₃, RT, overnight, 2.) 120 deg C, 2 h

2: 80 percent / POCl₃ / 0.5 h / Heating

With pyridine; ammonium hydroxide; trichlorophosphate;
DOI:10.1021/jm981012m

Reference yield:

: 98-88-4
benzoyl chloride

: 214417-22-8
4-chloro-2-phenylthieno[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) pyridine, 2.) 30percent NH₃ / 1.) CHCl₃, RT, overnight, 2.) 120 deg C, 2 h

2: 80 percent / POCl₃ / 0.5 h / Heating

With pyridine; ammonium hydroxide; trichlorophosphate;
DOI:10.1021/jm981012m