1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one

Base Information

Chemical Name:1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one
CAS No.:119304-98-2
Molecular Formula:C12H14O2
Molecular Weight:190.24
Hs Code.:
DSSTox Substance ID:DTXSID60557343
Mol file:119304-98-2.mol

Synonyms:119304-98-2;1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one;1-(chroman-4-yl)propan-2-one;1-(3,4-Dihydro-2H-1-benzopyran-4-yl)propan-2-one;(chroman-4-yl)acetone;4-acetonylchroman;DTXSID60557343;F53112

Suppliers and Price of 1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one

Chemical Property:

PSA：26.30000
LogP:2.53180
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:190.099379685
Heavy Atom Count:14
Complexity:212

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)CC1CCOC2=CC=CC=C12

Technology Process of 1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one

There total 5 articles about 1-(3,4-dihydro-2H-chromen-4-yl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 917-64-6
methyl magnesium iodide

: 119304-97-1
(chroman-4-yl)acetamide

: 119304-98-2
(chroman-4-yl)acetone

Guidance literature:: In diethyl ether; for 8h; Heating;
DOI:10.1248/cpb.36.3453

Reference yield:

: 491-37-2
2,3-dihydro-4H-1-benzopyran-4-one

: 119304-98-2
(chroman-4-yl)acetone

Guidance literature:: Multi-step reaction with 5 steps

2: 81 percent / 10percent KOH / methanol / 1 h / Heating

3: SOCl₂ / benzene / 3 h / Heating

4: 28percent aq. NH₃ / tetrahydrofuran / 1 h / Heating

5: 57 percent / diethyl ether / 8 h / Heating

With potassium hydroxide; ammonium hydroxide; thionyl chloride; In tetrahydrofuran; methanol; diethyl ether; benzene;
DOI:10.1248/cpb.36.3453

Reference yield:

: 121278-47-5
(3,4-dihydro-1(2H)-benzopyran-4-yl)ethanoyl chloride

: 119304-98-2
(chroman-4-yl)acetone

Guidance literature:: Multi-step reaction with 2 steps

1: 28percent aq. NH₃ / tetrahydrofuran / 1 h / Heating

2: 57 percent / diethyl ether / 8 h / Heating

With ammonium hydroxide; In tetrahydrofuran; diethyl ether;
DOI:10.1248/cpb.36.3453