7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin

Base Information Edit

Chemical Name:7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin
CAS No.:158722-23-7
Molecular Formula:C53H63NO13Si
Molecular Weight:950.168
Hs Code.:
Nikkaji Number:J883.808I
Mol file:158722-23-7.mol

Synonyms:158722-23-7;7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin;[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-2-benzoyloxy-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-triethylsilyloxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-15-yl] (4S,5R)-2,4-diphenyl-4,5-dihydro-1,3-oxazole-5-carboxylate;ZAXCJOQYACAQIY-RGZLSWIJSA-N;F12881;A883396;(1S)-4,10beta-Diacetoxy-2alpha-(benzoyloxy)-5beta,20-epoxy-1-hydroxy-7beta-(triethylsiloxy)-13alpha-[[[[(4S,5R)-2,4-diphenyl-4,5-dihydrooxazol]-5-yl]carbonyl]oxy]tax-11-en-9-one

Suppliers and Price of 7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin 97%
1g
$ 1131.00

Chemenu
7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin 97%
1g
$ 1066.00

Total 17 raw suppliers

Chemical Property of 7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin Edit

Chemical Property:

Melting Point:211-212 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point:893.9±65.0 °C(Predicted)
PKA:12.36±0.70(Predicted)
PSA：182.55000
Density:1.28±0.1 g/cm3(Predicted)
LogP:7.25550
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:17
Exact Mass:949.40686760
Heavy Atom Count:68
Complexity:1990

Purity/Quality:

98%,99%, ^*data from raw suppliers

7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC[Si](CC)(CC)OC1CC2C(CO2)(C3C1(C(=O)C(C4=C(C(CC(C3OC(=O)C5=CC=CC=C5)(C4(C)C)O)OC(=O)C6C(N=C(O6)C7=CC=CC=C7)C8=CC=CC=C8)C)OC(=O)C)C)OC(=O)C
Isomeric SMILES:CC[Si](CC)(CC)O[C@H]1C[C@@H]2[C@@](CO2)([C@@H]3[C@@]1(C(=O)[C@@H](C4=C([C@H](C[C@@]([C@H]3OC(=O)C5=CC=CC=C5)(C4(C)C)O)OC(=O)[C@H]6[C@@H](N=C(O6)C7=CC=CC=C7)C8=CC=CC=C8)C)OC(=O)C)C)OC(=O)C

Technology Process of 7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin

There total 23 articles about 7-(Triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 115437-21-3
7-(triethylsilyl)baccatin III

: 158722-22-6
(4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid

: 158722-23-7
7-(triethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydrooxazol-5-yl)carbonyl]baccatin

Guidance literature:: With 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; In toluene; for 0.5h; Ambient temperature;
DOI:10.1016/S0040-4039(00)60706-2