6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
• CAS No.: 107516-75-6
• Molecular Formula: C14H15NO4
• Molecular Weight: 261.277
• Hs Code.: 2933990090
• Mol file: 107516-75-6.mol

Synonyms:1H-Indole-2,6-dicarboxylic acid, diethyl ester (9CI);Indole-2,6-dicarboxylic acid, diethyl ester (6CI);

Chemical Property of 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 119-121℃
• Boiling Point: 420.183°C at 760 mmHg
• PKA: 13.84±0.30(Predicted)
• Flash Point: 207.92°C
• PSA: 68.39000
• Density: 1.24g/cm³
• LogP: 2.52130
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

Diethyl1H-Indole-2,6-dicarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

There total 9 articles about 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

ethyl 4-(3-ethoxy-2,3-dioxopropyl)-3-nitrobenzoate (861384-91-0) → diethyl 1H-indole-2,6-dicarboxylate (107516-75-6)

Guidance literature:

With acetic acid; zinc; In water; at 80 ℃; for 2h;

Reference yield:

indole-2,6-dicarboxylic acid (103027-97-0) → diethyl 1H-indole-2,6-dicarboxylate (107516-75-6)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01564a058

Reference yield:

6-(trifluoromethyl)-1H-indole-2-carboxylic acid (327-20-8) → diethyl 1H-indole-2,6-dicarboxylate (107516-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: etheric diazoethane solution

With Diazoethan; sodium hydroxide;

DOI:10.1021/ja01564a058

upstream raw materials:

indole-2,6-dicarboxylic acid

ethyl 4-(3-ethoxy-2,3-dioxopropyl)-3-nitrobenzoate

6-(trifluoromethyl)-1H-indole-2-carboxylic acid

ethyl 6-(trifluoromethyl)-1H-indole-2-carboxylate

Downstream raw materials:

1-(cyano-methyl-methyl)-1H-indole-2,6-dicarboxylic acid diethyl ester

N-(3-chlorophenyl)-1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indole-8-carboxamide

N-(5-benzyl-1,2-oxazol-3-yl)-1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indole-8-carboxamide

N-(2-carbamoylphenyl)-1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indole-8-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 107516-75-6 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send