Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate

Base Information Edit

Chemical Name:Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate
CAS No.:859854-67-4
Molecular Formula:C₁₈H₂₆N₂O₅
Molecular Weight:350.415
Hs Code.:
DSSTox Substance ID:DTXSID60705342
Wikidata:Q82638182
Mol file:859854-67-4.mol

Synonyms:1052715-76-0;Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate;(3R,4R)-BENZYL 3-(TERT-BUTOXYCARBONYLAMINO)-4-HYDROXYPIPERIDINE-1-CARBOXYLATE;benzyl (3R,4R)-4-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-1-carboxylate;859854-67-4;Benzyl (3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate;Benzyl (3R,4R)-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate;SCHEMBL4120261;DTXSID60705342;rel-Benzyl (3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate;ZOHDMZDTYNCUBC-HUUCEWRRSA-N;CS-0362882;S10991;Benzyl rel-(3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate;Benzylrel-(3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate;trans (+/-)-benzyl 3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate;trans(+/-)-benzyl 3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate

Suppliers and Price of Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate Edit

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:350.18417193
Heavy Atom Count:25
Complexity:457

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CN(CCC1O)C(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H]1CN(CC[C@H]1O)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate

There total 96 articles about Benzyl (3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: C₁₄H₁₆N₂O₄

: 859854-67-4,1549812-60-3
(trans)-benzyl 3-((tert-butoxycarbonyl)amino)-4-hydroxypiperidine-1-carboxylate

Guidance literature:: di-tert-butyl dicarbonate; C₁₄H₁₆N₂O₄; With dmap; triethylamine; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

With methanol; potassium carbonate; at 20 ℃;