Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy-

Base Information

Chemical Name:Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy-
CAS No.:873546-30-6
Molecular Formula:C25H35N5O4
Molecular Weight:469.584
Hs Code.:

Synonyms:4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N'-hydroxybenzamide oxime;

Suppliers and Price of Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy-

Chemical Property:

PSA：138.92000
LogP:4.55420

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy-

There total 5 articles about Benzenecarboximidamide, 4,4'-[1,4-piperidinediylbis(3,1-propanediyloxy)]bis[N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 873546-80-6
4-(3-{4-[3-(4-cyanophenoxy)propyl]-1-piperidinyl}propoxy)benzonitrile

: 873546-30-6
4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N'-hydroxybenzamidine

Guidance literature:: With hydroxylamine; In water; dimethyl sulfoxide; at 50 ℃; for 19h;

Reference yield:

: 873546-87-3
3-(4-cyanophenoxy)propyl methanesulfonate

: 873546-30-6
4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N'-hydroxybenzamidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydrogencarbonate; potassium iodide / N,N-dimethyl-formamide / 7 h / 20 - 70 °C

1.2: pH 1.0

1.3: 0.75 h / 0 - 20 °C / pH 10.0

2.1: triethylamine / tetrahydrofuran / 1.17 h / 20 °C

3.1: potassium carbonate / dimethyl sulfoxide / 2 h / 20 - 60 °C

4.1: hydroxylamine / water; dimethyl sulfoxide / 19 h / 50 °C

With hydroxylamine; sodium hydrogencarbonate; potassium carbonate; triethylamine; potassium iodide; In tetrahydrofuran; water; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 943150-81-0
3-{1-[3-(4-cyanophenoxy)propyl]-4-piperidinyl}propyl methanesulfonate

: 873546-30-6
4-{3-[4-(3-{4-[amino(hydroxyimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N'-hydroxybenzamidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 2 h / 20 - 60 °C

2: hydroxylamine / water; dimethyl sulfoxide / 19 h / 50 °C

With hydroxylamine; potassium carbonate; In water; dimethyl sulfoxide;