7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine

Base Information

Chemical Name:7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine
CAS No.:41102-25-4
Molecular Formula:C6HBrCl2N2S
Molecular Weight:283.963
Hs Code.:2934999090
ChEMBL ID:CHEMBL3236404
DSSTox Substance ID:DTXSID60592815
Nikkaji Number:J2.441.200H
Wikidata:Q82487131
Mol file:41102-25-4.mol

Synonyms:7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine;41102-25-4;7-Bromo-2,4-dichloro-thieno[3,2-d]pyrimidine;MFCD11869289;SCHEMBL1284962;CHEMBL3236404;DTXSID60592815;SELNIRJYLYMJKG-UHFFFAOYSA-N;AKOS015835733;PB31616;AS-42536;DA-42488;SY098467;CS-0050093;EN300-3270690;Z1269174802

Suppliers and Price of 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine
1 g
$ 375.00

Matrix Scientific
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine >95%
1g
$ 447.00

Matrix Scientific
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine >95%
250mg
$ 153.00

Crysdot
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine 95+%
250mg
$ 130.00

Crysdot
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine 95+%
1g
$ 328.00

Crysdot
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine 95+%
5g
$ 860.00

ChemScene
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine
1g
$ 750.00

ChemScene
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine
100mg
$ 225.00

ChemScene
7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine
250mg
$ 375.00

Chemenu
7-bromo-2,4-dichlorothieno[3,2-d]pyrimidine 97%
1g
$ 275.00

Total 28 raw suppliers

Chemical Property of 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine

Chemical Property:

Boiling Point:332.9±42.0 °C(Predicted)
PKA:-2.03±0.40(Predicted)
PSA：54.02000
Density:2.034±0.06 g/cm3(Predicted)
LogP:3.76060
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:281.84209
Heavy Atom Count:12
Complexity:185

Purity/Quality:

99%, ^*data from raw suppliers

7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C2=C(S1)C(=NC(=N2)Cl)Cl)Br
Uses 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine can be used for antiproliferative activities.

Technology Process of 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine

There total 7 articles about 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 41102-02-7
7-bromothieno[3,2-d]pyrimidine-2,4(1H,3H)-dione

: 41102-25-4
7-bromo-2,4-dichloroimidazo[2,1-f][1,2,4]triazine

Guidance literature:: With trichlorophosphate; at 110 ℃; for 24h;

Reference yield: 55.0%

: 7-bromothieno[3,2-d]pyrimidine-2,4-diol

: 41102-25-4
7-bromo-2,4-dichloroimidazo[2,1-f][1,2,4]triazine

Guidance literature:: With triethylamine hydrochloride; trichlorophosphate; at 0 - 110 ℃; for 8h; Sealed tube;

Reference yield:

: 16233-51-5
1H-thieno[3,2-d]pyrimidine-2,4-dione

: 41102-25-4
7-bromo-2,4-dichloroimidazo[2,1-f][1,2,4]triazine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / bromine / acetic acid / 48 h / 110 °C

2: 64 percent / POCl₃; N,N-diethylaniline / 3 h / Heating

With bromine; N,N-diethylaniline; trichlorophosphate; In acetic acid;
DOI:10.1016/j.tet.2007.01.075