(1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine

Base Information

Chemical Name:(1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine
CAS No.:210482-10-3
Molecular Formula:C19H22N2
Molecular Weight:278.397
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70448172
Nikkaji Number:J963.131C,J972.739F
Wikidata:Q82267136
Mol file:210482-10-3.mol

Synonyms:210482-10-3;EXO-6-[BIS(PHENYLMETHYL)AMINO]-3-AZABICYCLO[3.1.0]HEXANE;(1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine;(1R,5S,6s)-rel-N,N-Dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine;(1R,5S,6S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine;3-Azabicyclo[3.1.0]hexan-6-amine, N,N-bis(phenylmethyl)-, (1a,5a,6a)- (9CI);(1S,5R)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine;Rel-(1R,5S,6r)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine;starbld0015713;SCHEMBL7867639;SCHEMBL14087065;SCHEMBL14741312;DTXSID70448172;AKOS015950244;AS-33449;CS-0049360;(1alpha,5alpha)-N,N-Dibenzyl-3-azabicyclo[3.1.0]hexane-6alpha-amine;(1alpha,5alpha)-N,N-Dibenzyl-3-azabicyclo[3.1.0]hexane-6beta-amine

Suppliers and Price of (1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Azabicyclo[3.1.0]hexan-6-amine N,N-bis(phenylmethyl)-(1a,5a,6a)- (9CI)>95%
1g
$ 1042.00

Matrix Scientific
3-Azabicyclo[3.1.0]hexan-6-amine N,N-bis(phenylmethyl)-(1a,5a,6a)- (9CI)>95%
500mg
$ 607.00

Matrix Scientific
3-Azabicyclo[3.1.0]hexan-6-amine N,N-bis(phenylmethyl)-(1a,5a,6a)- (9CI)>95%
250mg
$ 360.00

Chemenu
(1R,5S,6s)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine 95+%
5g
$ 935.00

Chemenu
(1R,5S,6s)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine 95+%
1g
$ 328.00

Chemenu
(1R,5S,6s)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine 95+%
10g
$ 1276.00

Alichem
(1R,5S,6s)-rel-N,N-Dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine
5g
$ 960.40

AK Scientific
3-Azabicyclo[3.1.0]hexan-6-amine,N,N-bis(phenylmethyl)-,(1a,5a,6a)-(9CI)
250mg
$ 536.00

Activate Scientific
exo-6-[Bis(phenylmethyl)amino]-3-Azabicyclo[3.1.0]hexane 95+%
5 g
$ 1204.00

Activate Scientific
exo-6-[Bis(phenylmethyl)amino]-3-Azabicyclo[3.1.0]hexane 95+%
1 g
$ 422.00

Total 17 raw suppliers

Chemical Property of (1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine

Chemical Property:

Boiling Point:401.2±40.0 °C(Predicted)
PKA:10.90±0.40(Predicted)
PSA：15.27000
Density:1.14±0.1 g/cm3(Predicted)
LogP:3.23540
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:278.178298710
Heavy Atom Count:21
Complexity:301

Purity/Quality:

99%, ^*data from raw suppliers

3-Azabicyclo[3.1.0]hexan-6-amine N,N-bis(phenylmethyl)-(1a,5a,6a)- (9CI)>95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C(C2N(CC3=CC=CC=C3)CC4=CC=CC=C4)CN1
Isomeric SMILES:C1[C@@H]2[C@@H](C2N(CC3=CC=CC=C3)CC4=CC=CC=C4)CN1

Technology Process of (1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine

There total 3 articles about (1R,5S)-N,N-dibenzyl-3-azabicyclo[3.1.0]hexan-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 497163-57-2
tert-butyl (1R,5S,6s)-6-(N,N-dibenzylamino)-3-azabicyclo[3.1.0]hexane-3-carboxylate

: 210482-10-3
1α,5α,6α-6-dibenzylamino-3-azabicyclo[3.1.0]hexane

Guidance literature:: tert-butyl (1R,5S,6s)-6-(N,N-dibenzylamino)-3-azabicyclo[3.1.0]hexane-3-carboxylate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

With water; sodium hydrogencarbonate; In chloroform;

Reference yield: 56.0%

: 164799-14-8
3α,4β,5α-4-(dibenzylamino)-3,5-cyclopiperidine-4-carbonitrile

: 210165-65-4
1α,5α,6β-6-dibenzylamino-3-azabicyclo[3.1.0]hexane

: 210482-10-3
1α,5α,6α-6-dibenzylamino-3-azabicyclo[3.1.0]hexane

Guidance literature:: With ammonia; lithium; ethylamine; at 0 ℃; for 0.166667h;
DOI:10.1016/S0040-4020(98)00298-1

Reference yield:

: 5464-77-7
N,N-dibenzylformamide

: 210482-10-3
1α,5α,6α-6-dibenzylamino-3-azabicyclo[3.1.0]hexane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 90 percent / cyclohexylmagnesium bromide; MeMgCl; [Ti(OiPr)4] / tetrahydrofuran; diethyl ether / 0.25 h / Heating

2.1: CF₃COOH / 1 h / 20 °C

2.2: 98 percent / poly-4-vinylpyridine / methanol / 1 h

With titanium(IV) isopropylate; methylmagnesium chloride; trifluoroacetic acid; cyclohexylmagnesium bromide; In tetrahydrofuran; diethyl ether;
DOI:10.1002/1521-3765(20020816)8:16<3789::AID-CHEM3789>3.0.CO;2-R