6-Methoxyl-2-aMinobenzoxazol

Base Information

• Chemical Name: 6-Methoxyl-2-aMinobenzoxazol
• CAS No.: 13895-08-4
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.164
• Hs Code.: 2934999090
• Mol file: 13895-08-4.mol

Synonyms:6-methoxy-benzooxazol-2-ylamine;6-Methoxy-2-aminobenzoxazole;6-Methoxyl-2-aminobenzoxazol;

Chemical Property of 6-Methoxyl-2-aMinobenzoxazol

Chemical Property:

• PSA: 61.28000
• LogP: 1.99980

Purity/Quality:

99.90% ^*data from raw suppliers

6-Methoxybenzo[D]oxazol-2-Amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Methoxyl-2-aMinobenzoxazol

There total 6 articles about 6-Methoxyl-2-aMinobenzoxazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-cyano-N-phenyl-p-toluenesulfonamide (55305-43-6) + 2-amino-5-methoxyphenol (40925-70-0) → 6-methoxybenzo[d]oxazole-2-amine (13895-08-4)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; hexane; at 5 - 20 ℃; for 1h; Green chemistry;

DOI:10.1055/s-0034-1380166

Reference yield: 90.0%

1-amino-2-hydroxy-4-methoxybenzene hydrochloride (39547-15-4) + di(1H-imidazol-1-yl)methanimine (104619-51-4) → 6-methoxybenzo[d]oxazole-2-amine (13895-08-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 20h; Inert atmosphere; Reflux;

Reference yield: 85.0%

bromocyane (506-68-3) + 2-amino-5-methoxyphenol (40925-70-0) → 6-methoxybenzo[d]oxazole-2-amine (13895-08-4)

Guidance literature:

In ethanol; for 2h; Reflux;

DOI:10.1016/j.bmcl.2016.05.017

upstream raw materials:

6-methoxy-benzooxazole-2-sulfonic acid; potassium salt

N-cyano-N-phenyl-p-toluenesulfonamide

2-amino-5-methoxyphenol

3-methoxy-6-nitro-phenol