5-Methoxy-2-nitrophenol

Base Information

Chemical Name:5-Methoxy-2-nitrophenol
CAS No.:704-14-3
Molecular Formula:C7H7NO4
Molecular Weight:169.137
Hs Code.:29095000
European Community (EC) Number:621-062-0
NSC Number:1167
UNII:TQ53BN6LHX
DSSTox Substance ID:DTXSID20277212
Nikkaji Number:J246.510H
Wikidata:Q72517294
Mol file:704-14-3.mol

Synonyms:2-Hydroxy-4-methoxynitrobenzene;2-Nitro-5-methoxyphenol;3-Methoxy-6-nitrophenol;5-Methoxy-2-nitrophenol;NSC1167;

Suppliers and Price of 5-Methoxy-2-nitrophenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Methoxy-2-nitrophenol
5g
$ 460.00

TRC
5-Methoxy-2-nitrophenol
25g
$ 450.00

TRC
5-Methoxy-2-nitrophenol
500mg
$ 50.00

SynQuest Laboratories
5-Methoxy-2-nitrophenol
25 g
$ 212.00

SynQuest Laboratories
5-Methoxy-2-nitrophenol
10 g
$ 106.00

Matrix Scientific
5-Methoxy-2-nitrophenol 95%
5g
$ 55.00

Matrix Scientific
5-Methoxy-2-nitrophenol 95%
10g
$ 90.00

Matrix Scientific
5-Methoxy-2-nitrophenol 95%
25g
$ 178.00

Frontier Specialty Chemicals
5-Methoxy-2-nitrophenol 98%
1g
$ 153.00

Crysdot
5-Methoxy-2-nitrophenol 97%
100g
$ 295.00

Total 38 raw suppliers

Chemical Property of 5-Methoxy-2-nitrophenol

Chemical Property:

Appearance/Colour:yellow crystals or powder
Vapor Pressure:0.000764mmHg at 25°C
Melting Point:92-94 °C
Refractive Index:1.583
Boiling Point:297.4 °C at 760 mmHg
PKA:6.95±0.13(Predicted)
Flash Point:133.7 °C
PSA：75.28000
Density:1.367 g/cm³
LogP:1.83220
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:169.03750770
Heavy Atom Count:12
Complexity:167

Purity/Quality:

99% ^*data from raw suppliers

5-Methoxy-2-nitrophenol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 37/38-41-36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)[N+](=O)[O-])O
Uses 5-Methoxy-2-nitrophenol is a reagent in the synthesis of conformationally constrained spirocycles, which are used as CCR1 antagonists. 5-Methoxy-2-nitrophenol is also used in the preparation of phenylsulfonyl aminophenoxybenzoates which can serve as EP1 receptor antagonists.

Technology Process of 5-Methoxy-2-nitrophenol

There total 20 articles about 5-Methoxy-2-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 4920-84-7
2,4-dimethoxynitrobenzene

: 704-14-3
3-methoxy-6-nitro-phenol

Guidance literature:: 2,4-dimethoxynitrobenzene; With aluminum (III) chloride; In chloroform; at 60 ℃; for 1.5h;

With hydrogenchloride; water; In chloroform; at 20 ℃; regioselective reaction;
DOI:10.1080/00397910802633439