Ethyl 3-Oxo-3-(6-quinolyl)propanoate

Base Information

Chemical Name:Ethyl 3-Oxo-3-(6-quinolyl)propanoate
CAS No.:858646-09-0
Molecular Formula:C14H13NO3
Molecular Weight:243.25792
Hs Code.:2933499090
DSSTox Substance ID:DTXSID10461305
Wikidata:Q82285586
Mol file:858646-09-0.mol

Synonyms:858646-09-0;Ethyl 3-Oxo-3-(6-quinolyl)propanoate;Ethyl 3-oxo-3-(quinolin-6-yl)propanoate;ethyl 3-oxo-3-quinolin-6-ylpropanoate;ETHYL 3-OXO-3(QUINOLIN-6-YL)PROPANOATE;SCHEMBL12600101;DTXSID10461305;YSGRFRZNMXBSBW-UHFFFAOYSA-N;AC7694;MFCD07370067;AKOS012396370;SB70541;Ethyl3-oxo-3-(quinolin-6-yl)propanoate;SY015759;CS-0456302;FT-0735642

Suppliers and Price of Ethyl 3-Oxo-3-(6-quinolyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 3-oxo-3-(6-quinolyl)propanoate
5 g
$ 1232.00

Labseeker
ethyl3-oxo-3(quinolin-6-yl)propanoate 95
5g
$ 1467.00

Crysdot
Ethyl3-oxo-3-(quinolin-6-yl)propanoate 95+%
5g
$ 518.00

Chemenu
Ethyl3-oxo-3-(quinolin-6-yl)propanoate 95%
5g
$ 489.00

American Custom Chemicals Corporation
ETHYL-3-OXO-3-(QUINOLIN-6-YL)PROPIONATE 95.00%
10G
$ 2431.57

American Custom Chemicals Corporation
ETHYL-3-OXO-3-(QUINOLIN-6-YL)PROPIONATE 95.00%
5G
$ 1497.75

Alichem
Ethyl3-oxo-3-(quinolin-6-yl)propanoate
5g
$ 543.92

AK Scientific
Ethyl3-oxo-3-(6-quinolyl)propanoate
5g
$ 802.00

Total 7 raw suppliers

Chemical Property of Ethyl 3-Oxo-3-(6-quinolyl)propanoate

Chemical Property:

Boiling Point:379.2±17.0 °C(Predicted)
PKA:9.37±0.46(Predicted)
PSA：56.26000
Density:1.208±0.06 g/cm3(Predicted)
LogP:2.37070
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:243.08954328
Heavy Atom Count:18
Complexity:316

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 3-oxo-3-(6-quinolyl)propanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=CC2=C(C=C1)N=CC=C2

Technology Process of Ethyl 3-Oxo-3-(6-quinolyl)propanoate

There total 3 articles about Ethyl 3-Oxo-3-(6-quinolyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-17-5
ethanol

: 1404449-57-5
2,2-dimethyl-5-(quinoline-6-carbonyl)-1,3-dioxane-4,6-dione

: 858646-09-0
ethyl 3-oxo-3-(quinolin-6-yl)propanoate

Guidance literature:: Reflux;

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 858646-09-0
ethyl 3-oxo-3-(quinolin-6-yl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: boric acid; ferrous(II) sulfate heptahydrate; sulfuric acid; 4-nitro-benzoic acid / 140 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

3: Reflux

With dmap; ferrous(II) sulfate heptahydrate; sulfuric acid; boric acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-nitro-benzoic acid; In dichloromethane;

Reference yield:

: 10349-57-2
Quinoline-6-carboxylic acid

: 858646-09-0
ethyl 3-oxo-3-(quinolin-6-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

2: Reflux

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;