7-(Benzyloxy)indoline

Base Information

• Chemical Name: 7-(Benzyloxy)indoline
• CAS No.: 191730-78-6
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID40564696
• Wikidata: Q82449492
• Mol file: 191730-78-6.mol

Synonyms:7-(Benzyloxy)indoline;191730-78-6;7-phenylmethoxy-2,3-dihydro-1H-indole;7-(Benzyloxy)-2,3-dihydro-1H-indole;7-Benzyloxyindoline;7 -Benzyloxyindoline;SCHEMBL4716745;DTXSID40564696;JPWDYUMKWGMYDD-UHFFFAOYSA-N;AKOS016007277;SB65341;2,3-Dihydro-7-(phenylmethoxy)-1H-indole;EN300-23703449

Chemical Property of 7-(Benzyloxy)indoline

Chemical Property:

• Melting Point: 128-129℃
• PSA: 21.26000
• LogP: 3.37160
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 225.115364102
• Heavy Atom Count: 17
• Complexity: 237

Purity/Quality:

99% ^*data from raw suppliers

7-(Benzyloxy)indoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNC2=C1C=CC=C2OCC3=CC=CC=C3

Technology Process of 7-(Benzyloxy)indoline

There total 5 articles about 7-(Benzyloxy)indoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

7-benzyloxyindole (20289-27-4) → petroleum + 7-benzyloxyindoline (191730-78-6)

Guidance literature:

With sodium hydroxide; sodium cyanoborohydride; In acetic acid;

Reference yield: 86.0%

7-benzyloxyindole (20289-27-4) → 7-benzyloxyindoline (191730-78-6)

Guidance literature:

With sodium cyanoborohydride; acetic acid; at 0 - 20 ℃; Further stages; Inert atmosphere;

DOI:10.1039/c4ob00542b

Reference yield:

7-benzyloxy-2-indolinone (74864-81-6) → 7-benzyloxyindoline (191730-78-6)

Guidance literature:

With tetrahydrofuran; lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01651a001

upstream raw materials:

7-benzyloxy-2-indolinone

3-benzyloxy-2-nitrophenyl-acetic acid

7-benzyloxyindole

Downstream raw materials:

N-(7-benzyloxy-2,3-dihydro-indole-1-carbothioyl)-benzamide