7-(trifluoromethyl)-1H-indole

Base Information

Chemical Name:7-(trifluoromethyl)-1H-indole
CAS No.:172217-02-6
Molecular Formula:C₉H₆F₃N
Molecular Weight:185.149
Hs Code.:
European Community (EC) Number:865-164-5
DSSTox Substance ID:DTXSID00439558
Nikkaji Number:J1.198.317K
Wikidata:Q82255538
Mol file:172217-02-6.mol

Synonyms:7-(trifluoromethyl)-1H-indole;172217-02-6;7-trifluoromethyl-1H-indole;7-(Trifluoromethyl)indole;MFCD09954769;SCHEMBL593971;DTXSID00439558;AKOS006312264;CS-W005730;SB34232;DS-17672;SY033205;FT-0763136;EN300-188856;F15639;A881889;Z1198266436

Suppliers and Price of 7-(trifluoromethyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
7-(trifluoromethyl)-1H-indole 95
5g
$ 1633.00

J&W Pharmlab
7-Trifluoromethyl-1H-indole 96%
500mg
$ 249.00

Crysdot
7-(Trifluoromethyl)-1H-indole 97%
1g
$ 257.00

Chemenu
7-(trifluoromethyl)-1H-indole 95%+
1g
$ 243.00

American Custom Chemicals Corporation
7-(TRIFLUOROMETHYL)-1H-INDOLE 95.00%
5MG
$ 502.65

Ambeed
7-(Trifluoromethyl)-1H-indole 97%
5g
$ 881.00

Ambeed
7-(Trifluoromethyl)-1H-indole 97%
250mg
$ 103.00

Ambeed
7-(Trifluoromethyl)-1H-indole 97%
100mg
$ 64.00

Ambeed
7-(Trifluoromethyl)-1H-indole 97%
1g
$ 257.00

AK Scientific
7-(Trifluoromethyl)-1H-indole
1g
$ 406.00

Total 25 raw suppliers

Chemical Property of 7-(trifluoromethyl)-1H-indole

Chemical Property:

Vapor Pressure:0.024mmHg at 25°C
Refractive Index:1.556
Boiling Point:256.676°C at 760 mmHg
PKA:15.16±0.30(Predicted)
Flash Point:109.034°C
PSA：15.79000
Density:1.368g/cm³
LogP:3.18670
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:185.04523368
Heavy Atom Count:13
Complexity:190

Purity/Quality:

99%, ^*data from raw suppliers

7-(trifluoromethyl)-1H-indole 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)C(F)(F)F)NC=C2

Technology Process of 7-(trifluoromethyl)-1H-indole

There total 4 articles about 7-(trifluoromethyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 172216-98-7
7-(trifluoromethyl)-1H-indole-2-carboxylic acid

: 172217-02-6
7-(trifluoromethyl)indole

Guidance literature:: With copper chromite; In quinoline; at 200 - 210 ℃; for 0.75h;
DOI:10.1248/cpb.43.1281

Reference yield: 56.0%

: 384-22-5
2-nitrobenzotrifluoride

: 1826-67-1
vinyl magnesium bromide

: 172217-02-6
7-(trifluoromethyl)indole

Guidance literature:: In tetrahydrofuran; at -45 - -40 ℃;
DOI:10.1055/s-1999-2900

Reference yield:

: 120-72-9
indole

: 887144-94-7
Togni's reagent II

: 51310-54-4
2-(trifluoromethyl)indole

: 51310-55-5
3-(trifluoromethyl)-1H-indole

: 172217-02-6
7-(trifluoromethyl)indole

Guidance literature:: With iron(II) chloride; In dichloromethane; at 35 ℃; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1002/chem.201406333