3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Base Information

Chemical Name:3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid
CAS No.:31282-90-3
Molecular Formula:C₁₂H₁₅BrO₄
Molecular Weight:303.153
Hs Code.:
Mol file:31282-90-3.mol

Synonyms:(2-bromo-4-ethoxy-5-methoxyphenyl)propanoic acid;Benzenepropanoic acid, 2-bromo-4-ethoxy-5-methoxy-;3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Suppliers and Price of 3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Chemical Property:

PSA：55.76000
LogP:2.87360

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

There total 4 articles about 3-(2-Bromo-4-ethoxy-5-methoxyphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 2033-24-1
cycl-isopropylidene malonate

: 56517-31-8
2-bromo-4-ethoxy-5-methoxybenzaldehyde

: 31282-90-3
3-(2-bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Guidance literature:: cycl-isopropylidene malonate; 2-bromo-4-ethoxy-5-methoxybenzaldehyde; With formic acid; triethylamine; at 100 ℃;

With hydrogenchloride; water; pH=Ca. 1; Cooling with ice;
DOI:10.1002/jhet.3085

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 31282-90-3
3-(2-bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 20 °C

2.1: bromine / acetic acid / 20 °C

3.1: formic acid; triethylamine / 100 °C

3.2: pH Ca_. 1 / Cooling with ice

With formic acid; bromine; potassium carbonate; triethylamine; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/jhet.3085

Reference yield:

: 120-25-2
4-ethoxy-3-methoxybenzaldehyde

: 31282-90-3
3-(2-bromo-4-ethoxy-5-methoxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / acetic acid / 20 °C

2.1: formic acid; triethylamine / 100 °C

2.2: pH Ca_. 1 / Cooling with ice

With formic acid; bromine; triethylamine; In acetic acid;
DOI:10.1002/jhet.3085