(3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Base Information

Chemical Name:(3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid
CAS No.:1069113-47-8
Molecular Formula:C13H21NO4
Molecular Weight:255.31
Hs Code.:
Mol file:1069113-47-8.mol

Synonyms:7-carboxy-3-azabicyclooctane;7-carboxy-1-methyl-1H-imidazo[1,2-b]pyrazole;7-carboethoxyamido-4-methylcoumarin-3-acetic acid ethyl ester;7-[(Ethoxycarbonyl)amino]-4-methyl-2-oxo-2H-1-benzopyran-3-acetic acid ethyl ester;

Suppliers and Price of (3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
cis-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylicacid 95+%
1g
$ 1452.00

Crysdot
cis-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylicacid 95+%
100mg
$ 362.00

Chemenu
(3aR,6aS)-2-[(2-methylpropan-2-yl)oxycarbonyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-5-carboxylicacid 95%+
1g
$ 460.00

American Custom Chemicals Corporation
(3AR,5R,6AS)-2-(TERT-BUTOXYCARBONYL)OCTAHYDROCYCLOPENTA[C]PYRROLE-5-CARBOXYLIC ACID 95.00%
5MG
$ 497.42

Alichem
cis-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylicacid
1g
$ 1521.52

Alichem
cis-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylicacid
250mg
$ 590.85

Total 10 raw suppliers

Chemical Property of (3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Chemical Property:

Boiling Point:386.0±35.0 °C(Predicted)
PKA:4.69±0.20(Predicted)
PSA：66.84000
Density:1.196±0.06 g/cm3(Predicted)
LogP:1.90200

Purity/Quality:

99%, ^*data from raw suppliers

cis-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

There total 5 articles about (3aR,5r,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3aR,6aS)-tert-butyl 5-cyanohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

: 1069113-47-8,1401464-09-2
(3aR,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Guidance literature:: With potassium hydroxide; In 1,2-dimethoxyethane; at 115 ℃; for 2h;

Reference yield:

: 146231-54-1
(3aR,6aS)-tert-butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

: 1069113-47-8,1401464-09-2
(3aR,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / 1,2-dimethoxyethane; ethanol / 0 - 60 °C / Inert atmosphere

2: potassium hydroxide / 1,2-dimethoxyethane / 2 h / 115 °C

With potassium tert-butylate; potassium hydroxide; In 1,2-dimethoxyethane; ethanol;

Reference yield:

: 2049-80-1
(2-propenyl)propanedioic acid diethyl ester

: 1069113-47-8,1401464-09-2
(3aR,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride; N-iodo-succinimide

2: bis(tri-n-butyltin) / Irradiation

3: hydrogenchloride / Reflux

With hydrogenchloride; N-iodo-succinimide; bis(tri-n-butyltin); sodium hydride;
DOI:10.1016/j.bmcl.2013.04.058