2-aMino-3-(Methoxycarbonyl)pyrazine 1-oxide

Base Information

• Chemical Name: 2-aMino-3-(Methoxycarbonyl)pyrazine 1-oxide
• CAS No.: 17149-35-8
• Molecular Formula: C6H7N3O3
• Molecular Weight: 169.14
• Hs Code.: 2933990090
• Mol file: 17149-35-8.mol

Synonyms:3-Aminopyrazin-2-carbonsaeuremethylester-4-oxid;QC-1010;3-amino-4-oxy-pyrazine-2-carboxylic acid methyl ester;

Chemical Property of 2-aMino-3-(Methoxycarbonyl)pyrazine 1-oxide

Chemical Property:

• PSA: 88.20000
• LogP: -0.51380

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-3-(methoxycarbonyl)pyrazine1-oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-aMino-3-(Methoxycarbonyl)pyrazine 1-oxide

There total 3 articles about 2-aMino-3-(Methoxycarbonyl)pyrazine 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl 3-amino-2-pyrazinecarboxylate (16298-03-6) → 2-amino-3-(methoxycarbonyl)pyrazine1-oxide (17149-35-8)

Guidance literature:

With dihydrogen peroxide; In ethanol; water; at 20 ℃; for 3h;

DOI:10.1080/14756366.2018.1516652

Reference yield:

3-aminopyrazinoic acid (5424-01-1) → 2-amino-3-(methoxycarbonyl)pyrazine1-oxide (17149-35-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; toluene / 0.5 h / 0 °C

2: dihydrogen peroxide / ethanol; water / 3 h / 20 °C

With dihydrogen peroxide; In methanol; ethanol; water; toluene;

DOI:10.1080/14756366.2018.1516652

Reference yield:

→ 2-amino-3-(methoxycarbonyl)pyrazine1-oxide (17149-35-8)

Guidance literature:

3-Aminopyrazin-2-carbonsaeuremethylester u. m-Chlorperbenzoesaeure;

upstream raw materials:

3-aminopyrazinoic acid

Methyl 3-amino-2-pyrazinecarboxylate

Downstream raw materials:

3-amino-5-chloro-pyrazine-2-carboxylic acid methyl ester

3-amino-6-chloropyrazine-2-carboxylic acid methyl ester