Balicatib

Base Information

Chemical Name:Balicatib
CAS No.:354813-19-7
Molecular Formula:C23H33N5O2
Molecular Weight:411.547
Hs Code.:2933599090
UNII:E00MVC7O57
DSSTox Substance ID:DTXSID10188989
Nikkaji Number:J2.552.684H
Wikidata:Q27074857
NCI Thesaurus Code:C79521
Pharos Ligand ID:KHGS5YLANK5P
Metabolomics Workbench ID:153266
ChEMBL ID:CHEMBL371064
Mol file:354813-19-7.mol

Synonyms:balicatib;N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide

Suppliers and Price of Balicatib

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Balicatib
50mg
$ 580.00

TRC
Balicatib
10mg
$ 140.00

Tocris
Balicatib ≥98%(HPLC)
10
$ 163.00

Tocris
Balicatib ≥98%(HPLC)
50
$ 615.00

DC Chemicals
Balicatib >98%
1 g
$ 1600.00

Crysdot
Balicatib 98+%
50mg
$ 210.00

Crysdot
Balicatib 98+%
100mg
$ 315.00

ChemScene
Balicatib 99.07%
5mg
$ 65.00

ChemScene
Balicatib 99.07%
10mg
$ 120.00

Cayman Chemical
Balicatib ≥98%
10mg
$ 135.00

Total 27 raw suppliers

Chemical Property of Balicatib

Chemical Property:

Appearance/Colour:white to off-white solid powder
Boiling Point:687.4±55.0 °C(Predicted)
PKA:13.23±0.20(Predicted)
PSA：88.47000
Density:1.19±0.1 g/cm3(Predicted)
LogP:3.07578
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:411.26342531
Heavy Atom Count:30
Complexity:621

Purity/Quality:

99%, ^*data from raw suppliers

Balicatib ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3(CCCCC3)C(=O)NCC#N
Recent ClinicalTrials:Safety/Efficacy of Balicatib (AAE581) in Adults With Osteoarthritis of the Knee
Recent EU Clinical Trials:An observational, safety follow-up extension to studies 2203 and 2203E1 to assess the safety of AAE581 in postmenopausal women with osteopenia/osteoporosis
Uses Balicatib is a potent inhibitor of Cathepsin K (Cat K), a lysosomal cysteine protease, for the treatment of osteoporosis.

Technology Process of Balicatib

There total 1 articles about Balicatib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: