7-Chloroquinoline-8-carboxylic acid

Base Information

Chemical Name:7-Chloroquinoline-8-carboxylic acid
CAS No.:87293-44-5
Molecular Formula:C₁₀H₆ClNO₂
Molecular Weight:207.616
Hs Code.:
DSSTox Substance ID:DTXSID50597511
Wikidata:Q82493067
Mol file:87293-44-5.mol

Synonyms:7-CHLOROQUINOLINE-8-CARBOXYLIC ACID;87293-44-5;7-Chloro-8-quinolinecarboxylic acid;8-Quinolinecarboxylic acid, 7-chloro-;SCHEMBL9197665;DTXSID50597511;SB70985;7-CHLOROQUINOLINE-8-CARBOXYLICACID;DB-307340;CS-0260769;EN300-75834;F82004;A937785

Suppliers and Price of 7-Chloroquinoline-8-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Chloro-8-quinolinecarboxylicacid
25mg
$ 165.00

Matrix Scientific
7-Chloro-8-quinolinecarboxylic acid 97%
1g
$ 883.00

AK Scientific
7-Chloroquinoline-8-carboxylicacid
500mg
$ 951.00

Total 4 raw suppliers

Chemical Property of 7-Chloroquinoline-8-carboxylic acid

Chemical Property:

PSA：50.19000
LogP:2.58640
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:207.0087061
Heavy Atom Count:14
Complexity:234

Purity/Quality:

99% ^*data from raw suppliers

7-Chloro-8-quinolinecarboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C(C=C2)Cl)C(=O)O)N=C1
Uses 7-Chloro-8-quinolinecarboxylic acid is an impurity of Quinclorac (Q670300).

Technology Process of 7-Chloroquinoline-8-carboxylic acid

There total 3 articles about 7-Chloroquinoline-8-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

: 78941-93-2
7-Chloro-8-methylquinoline

: 87293-44-5
7-chloro-8-quinolinecarboxylic acid

Guidance literature:: With vanadia; ozone; sodium bromide; cobalt(II) chloride; In acetic acid; at 100 ℃; Reagent/catalyst; Solvent;

Reference yield:

: 87-60-5
3-chloro-2-methylbenzenamine

: 87293-44-5
7-chloro-8-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; water; sodium iodide / 7 h / 120 - 140 °C

1.2: 1 h / 30 - 120 °C / pH 9 - 10

2.1: oxygen; N-hydroxyphthalimide; 2,2'-azobis(isobutyronitrile) / acetonitrile / 9 h / 90 °C / 30003 Torr

With N-hydroxyphthalimide; 2,2'-azobis(isobutyronitrile); sulfuric acid; water; oxygen; sodium iodide; In acetonitrile;