Osu 6162 hydrochloride

Base Information

Chemical Name:Osu 6162 hydrochloride
CAS No.:156907-84-5
Molecular Formula:C15H23NO2S.ClH
Molecular Weight:317.879
Hs Code.:
European Community (EC) Number:689-437-1
UNII:V5SBJBUJW6
DSSTox Substance ID:DTXSID40431531
Wikipedia:OSU-6162
Mol file:156907-84-5.mol

Synonyms:(S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine hydrochloride;3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine;PNU 96391;PNU-96391;PNU96391

Suppliers and Price of Osu 6162 hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
OSU6162 hydrochloride
5mg
$ 90.00

Tocris
OSU6162 hydrochloride ≥98%(HPLC)
50
$ 777.00

Tocris
OSU6162 hydrochloride ≥98%(HPLC)
10
$ 182.00

Sigma-Aldrich
OSU6162 hydrochloride ≥98% (HPLC)
5mg
$ 122.00

Sigma-Aldrich
OSU6162 hydrochloride ≥98% (HPLC)
25mg
$ 463.00

ApexBio Technology
OSU6162 hydrochloride
10mg
$ 266.00

ApexBio Technology
OSU6162 hydrochloride
50mg
$ 1141.00

American Custom Chemicals Corporation
OSU 6162 HYDROCHLORIDE 95.00%
5MG
$ 499.27

Total 7 raw suppliers

Chemical Property of Osu 6162 hydrochloride

Chemical Property:

Vapor Pressure:8.04E-08mmHg at 25°C
Boiling Point:436.5°C at 760 mmHg
Flash Point:217.8°C
PSA：45.76000
LogP:4.50020
Storage Temp.:Store at +4°C
Solubility.:H2O: ≥16mg/mL
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:317.1216279
Heavy Atom Count:20
Complexity:374

Purity/Quality:

98%Min ^*data from raw suppliers

OSU6162 hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCCC(C1)C2=CC(=CC=C2)S(=O)(=O)C.Cl
Isomeric SMILES:CCCN1CCC[C@H](C1)C2=CC(=CC=C2)S(=O)(=O)C.Cl
Uses OSU 6162 Hydrochloride is a weak dopamine D2 receptor antagonist. It is a salt analogue of (-)-OSU (O006162).

Technology Process of Osu 6162 hydrochloride

There total 7 articles about Osu 6162 hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-(-)-3-(3-methanesulfonyl)phenyl-1-propylpiperidine

: 156907-84-5
[3H]-(-)-OSU 6162 hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; ethyl acetate; at 10 ℃; for 1.5h; Inert atmosphere; Large scale;
DOI:10.1021/op025620u

Reference yield:

: 3-(3-methanesulfonylphenyl)-pyridine

: 156907-84-5
[3H]-(-)-OSU 6162 hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: hydrogen; platinum on carbon / water; phosphoric acid / 18 h / 98 °C / 3102.97 Torr / Inert atmosphere; Autoclave; Large scale

2: methanol / 0.5 h / 70 °C / Inert atmosphere; Large scale

3: sodium hydroxide / water; dichloromethane / Inert atmosphere; Cooling; Large scale

4: sodium tetrahydroborate / tetrahydrofuran / -5 - 63 °C / Inert atmosphere; Large scale

5: hydrogenchloride / ethyl acetate; ethanol / 1.5 h / 10 °C / Inert atmosphere; Large scale

With hydrogenchloride; sodium tetrahydroborate; platinum on carbon; hydrogen; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; phosphoric acid; water; ethyl acetate;
DOI:10.1021/op025620u

Reference yield:

: 160866-61-5
3-(3-methanesulfonylphenyl)piperidine

: 156907-84-5
[3H]-(-)-OSU 6162 hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: methanol / 0.5 h / 70 °C / Inert atmosphere; Large scale

2: sodium hydroxide / water; dichloromethane / Inert atmosphere; Cooling; Large scale

3: sodium tetrahydroborate / tetrahydrofuran / -5 - 63 °C / Inert atmosphere; Large scale

4: hydrogenchloride / ethyl acetate; ethanol / 1.5 h / 10 °C / Inert atmosphere; Large scale

With hydrogenchloride; sodium tetrahydroborate; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1021/op025620u